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SEPTIN10 Knockout Cell Lines

Gene: SEPTIN10

Official Full Name: septin 10provided by HGNC

Gene Summary: This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. A pseudogene for this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22011 SEPTIN10 Knockout cell line (HeLa) Human SEPTIN10 1:3~1:6 Negative Online Inquiry
KO22012 SEPTIN10 Knockout cell line (HCT 116) Human SEPTIN10 1:2~1:4 Negative Online Inquiry
KO22013 SEPTIN10 Knockout cell line (HEK293) Human SEPTIN10 1:3~1:6 Negative Online Inquiry
KO22014 SEPTIN10 Knockout cell line (A549) Human SEPTIN10 1:3~1:4 Negative Online Inquiry

Background

SEPTIN10 Gene Knockout Cell Lines are advanced, genetically modified cell lines specifically engineered to lack the function of the SEPTIN10 gene, which plays a pivotal role in cellular processes such as cytokinesis, membrane dynamics, and cytoskeletal organization. These cell lines are invaluable tools for researchers seeking to elucidate the biological pathways influenced by SEPTIN10 and its involvement in various diseases, including cancer, neurodegeneration, and infectious diseases.

The primary function of the SEPTIN10 gene is to participate in the assembly of septin filaments, which are crucial for maintaining cellular integrity and facilitating the proper segregation of chromosomes during cell division. By employing CRISPR-Cas9 technology, these cell lines allow for precise editing, providing a clear window into the gene's role and the cellular consequences of its absence. Researchers can investigate altered cellular behaviors, cytokinetic failures, and the dysregulation of signaling pathways in the context of SEPTIN10 knockout, thus advancing our understanding of its pathophysiological implications.

The scientific importance of SEPTIN10 Gene Knockout Cell Lines cannot be overstated. In research settings, these lines empower scientists to explore gene function and establish connections between septin dysfunction and disease phenotypes. In clinical applications, they can be used to screen potential therapeutic agents or devise gene-targeted therapies that aim to reverse the effects of SEPTIN10 abnormalities.

Compared to traditional methods of gene investigation, the use of our specialized knockout cell lines provides several advantages: they offer enhanced specificity, reproducibility, and the capability for rapid screening against various interventions, leading to more robust data generation. Additionally, the convenience of ready-to-use cell lines significantly reduces the development time for experiments, enabling researchers to focus on progressing their studies.

For researchers and clinicians, the SEPTIN10 Gene Knockout Cell Lines represent a critical asset in the pursuit of innovative solutions to pressing biological challenges. Our commitment to providing high-quality, reliable products stems from our extensive expertise in molecular biology and genetic engineering. With a robust portfolio and a focus on cutting-edge research tools, we empower the scientific community to push the boundaries of knowledge and therapeutic advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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