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SEMA3G Knockout Cell Lines

Gene: SEMA3G

Official Full Name: semaphorin 3Gprovided by HGNC

Gene Summary: The transcription of this gene is activated by PPAR-gamma, and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14230 SEMA3G Knockout cell line (HCT 116) Human SEMA3G 1:2~1:4 Negative Online Inquiry
KO14231 SEMA3G Knockout cell line (HEK293) Human SEMA3G 1:3~1:6 Negative Online Inquiry

Background

SEMA3G Gene Knockout Cell Lines are genetically modified cell models specifically engineered for the targeted disruption of the semaphorin 3G gene. Semaphorins are a family of proteins known to play critical roles in cellular signaling and migration, and SEMA3G has been implicated in various physiological processes, including neuronal development, immune responses, and tumor progression. By employing CRISPR/Cas9 gene-editing technology, these cell lines enable researchers to investigate the specific functions of SEMA3G, elucidating its role in disease mechanisms and offering a compelling route for potential therapeutic interventions.

The primary function of the SEMA3G Gene Knockout Cell Lines is to serve as a cellular platform for studying the consequences of SEMA3G loss of function. Upon knockout of the gene, the resultant cells exhibit distinct phenotypic and molecular changes that can be systematically analyzed. Researchers can assess alterations in cell behavior, signaling pathways, and interactions with the extracellular matrix, thereby uncovering potential mechanistic insights relevant to cancer biology, neurodevelopmental disorders, and chronic inflammatory conditions.

The scientific importance of SEMA3G Gene Knockout Cell Lines lies in their utility in fundamental research and translational studies. In clinical settings, they offer a valuable tool for drug screening and biomarker discovery, enhancing our understanding of how SEMA3G influences both tumor microenvironments and neuronal pathways. Furthermore, these cell lines are indispensable in developing targeted therapies that could modulate SEMA3G activity.

Compared to conventional gene-editing methods or other models, SEMA3G Gene Knockout Cell Lines provide precise genetic modifications and reproducibility in experimental designs. Their robustness and reliability make them invaluable for cutting-edge research, setting them apart from alternative products in the market.

For researchers and clinicians alike, the SEMA3G Gene Knockout Cell Lines represent a powerful resource for elucidating biological processes and developing innovative therapeutic approaches. We take pride in our company’s expertise in creating high-quality biological products, ensuring that our clientele has access to the most advanced tools necessary for scientific exploration and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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