Gene: SEC22A
Official Full Name: SEC22 homolog A, vesicle trafficking proteinprovided by HGNC
Gene Summary: The protein encoded by this gene belongs to the member of the SEC22 family of vesicle trafficking proteins. This protein has similarity to rat SEC22 and may act in the early stages of the secretory pathway. [provided by RefSeq, Nov 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27939 | SEC22A Knockout cell line (HeLa) | Human | SEC22A | 1:3~1:6 | Negative | Online Inquiry |
KO27940 | SEC22A Knockout cell line (HCT 116) | Human | SEC22A | 1:2~1:4 | Negative | Online Inquiry |
KO27941 | SEC22A Knockout cell line (HEK293) | Human | SEC22A | 1:3~1:6 | Negative | Online Inquiry |
KO27942 | SEC22A Knockout cell line (A549) | Human | SEC22A | 1:3~1:4 | Negative | Online Inquiry |
SEC22A Gene Knockout Cell Lines are specially engineered cellular models designed to explore the functional role of the SEC22A gene, which is implicated in intracellular trafficking and vesicular transport mechanisms. Utilizing CRISPR-Cas9 technology, these cell lines have been precisely modified to silence the SEC22A gene, allowing researchers to investigate its role in a variety of biological processes, including secretion, membrane fusion, and cellular stress responses.
The primary function of SEC22A involves the maturation and transport of proteins within the endoplasmic reticulum and Golgi apparatus, crucial for maintaining cellular homeostasis. By utilizing these knockout cell lines, researchers can dissect the molecular pathways affected by the absence of SEC22A, leading to insights into pathologies associated with disrupted vesicular trafficking, such as neurodegenerative diseases and cancer.
The scientific importance of SEC22A Gene Knockout Cell Lines extends to their applications in both basic and translational research. These cell lines provide a powerful tool for drug discovery, enabling the identification of novel therapeutic targets and the evaluation of pharmaceutical efficacy through gene functionality assessment. They also hold potential in gene therapy research that aims to restore normal cellular functions in diseases linked to SEC22A dysregulation.
Compared to conventional cell lines, SEC22A Gene Knockout Cell Lines offer a unique advantage in specificity and reliability, reducing off-target effects associated with other gene silencing techniques. Their easy integration into existing research setups enhances their versatility, making them suitable for various applications ranging from pharmacological assays to mechanistic studies.
This product is invaluable to researchers and clinicians aiming to deepen their understanding of cellular transport processes and their implications in health and disease. The ability to systematically examine the consequences of SEC22A loss equips scientists with the necessary framework to develop innovative interventions.
Our company prides itself on a robust foundation in genetic engineering and cell line development, delivering high-quality biological products tailored for cutting-edge research and therapeutic applications.
Please note that all services are for research use only. Not intended for any clinical use.
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