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SDR16C5 Knockout Cell Lines

Gene: SDR16C5

Official Full Name: short chain dehydrogenase/reductase family 16C member 5provided by HGNC

Gene Summary: This gene encodes a member of the short-chain alcohol dehydrogenase/reductase superfamily of proteins and is involved in the oxidation of retinol to retinaldehyde. The encoded protein is associated with the endoplasmic reticulum and is predicted to contain three transmembrane helices, suggesting that it is an integral membrane protein. It recognizes all-trans-retinol and all-trans-retinaldehyde as substrates and exhibits a strong preference for NAD(+)/NADH as cofactors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14251 SDR16C5 Knockout cell line (HCT 116) Human SDR16C5 1:2~1:4 Negative Online Inquiry

Background

SDR16C5 Gene Knockout Cell Lines are advanced, genetically engineered cell models specifically designed to study the role of the SDR16C5 gene, which is implicated in various physiological and pathological processes. These cell lines have undergone targeted gene knockout using CRISPR/Cas9 technology, leading to the precise disruption of the SDR16C5 gene, allowing researchers to elucidate its functions and interactions within cellular pathways.

The primary function of SDR16C5 gene knockout cell lines lies in their ability to facilitate studies on gene function, metabolic pathways, and the impact of gene disruption on cellular behavior. By analyzing differences in biochemical and physiological characteristics between knockout and wild-type cells, researchers can gain insights into the gene’s role in metabolism, stress responses, and disease mechanisms. The use of these cell lines helps to advance our understanding of SDR16C5's contributions to disorders, providing a powerful tool for pharmacological studies and biomarker discovery.

In research and clinical settings, the SDR16C5 knockout cell lines serve as invaluable models for drug testing and validation. Their specificity allows for more accurate evaluations of therapeutic candidates targeting metabolic dysregulations associated with SDR16C5, which can have implications in areas such as cancer research and metabolic diseases. Compared to alternative methods, such as transient transfection, these knockout lines provide stable and reproducible results, dramatically enhancing experimental reliability.

For researchers and clinicians, the SDR16C5 Gene Knockout Cell Lines represent a significant advance in modeling human cellular responses, enabling groundbreaking discoveries. The ability to create tailored research models with unparalleled precision is crucial for addressing the complexities of gene function in vivo. Our company’s expertise in genetic engineering and cellular biology ensures that these cell lines are produced under stringent quality control measures, providing researchers with reliable and high-quality resources for their studies.

Please note that all services are for research use only. Not intended for any clinical use.

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