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SDK2 Knockout Cell Lines

Gene: SDK2

Official Full Name: sidekick cell adhesion molecule 2provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01726 SDK2 Knockout cell line (HEK293) Human SDK2 1:3~1:6 Negative Online Inquiry

Background

SDK2 Gene Knockout Cell Lines are a cutting-edge biological research tool designed to facilitate the exploration of the SDK2 gene's function and its implications in various cellular processes. These cell lines are engineered through CRISPR-Cas9 technology to create knockout variants, enabling researchers to study gene expression, protein interactions, and cellular responses in the absence of SDK2 activity. By silencing this gene, scientists can gain insights into its role in cellular signaling pathways, developmental biology, and disease mechanisms, particularly in cancers and neurodegenerative disorders.

The primary function of SDK2 knockout cell lines lies in their ability to provide a controlled environment for the investigation of gene function. By removing SDK2, researchers can delineate the compensatory mechanisms that may be activated and assess how the loss of this gene affects cellular behaviors such as proliferation, differentiation, and apoptosis. This nuanced understanding is crucial for advancing therapeutic strategies targeting related pathways in various diseases.

In scientific and clinical settings, these knockout cell lines hold immense value. They serve as vital tools in drug discovery, toxicity testing, and the elucidation of molecular pathways that could inform future treatment protocols. Their reproducibility and specificity can empower researchers to make clearer conclusions and develop more effective interventions.

Compared to traditional gene knockdown methods, such as RNA interference, SDK2 knockout cell lines provide a more permanent solution with fewer off-target effects, thus ensuring more reliable results. Additionally, these cell lines are compatible with a wide array of high-throughput screening assays, further enhancing their utility in facilitating rapid scientific advancements.

Given our company’s commitment to delivering high-quality biological reagents and tools for life sciences research, SDK2 Gene Knockout Cell Lines exemplify our expertise in providing researchers and clinicians with innovative resources vital for advancing their work. This product not only enriches scientific inquiry but also stands as a testament to our dedication to enabling breakthroughs in biology and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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