Gene: SDK1
Official Full Name: sidekick cell adhesion molecule 1provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains six immunoglobulin-like domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27330 | SDK1 Knockout cell line (HEK293) | Human | SDK1 | 1:3~1:6 | Negative | Online Inquiry |
SDK1 Gene Knockout Cell Lines are a specially developed biological tool designed for the functional study of the SDK1 gene (also known as Syndecan-1). These cell lines utilize CRISPR-Cas9 gene editing technology to effectively knock out the SDK1 gene, allowing researchers to investigate its role in cellular processes such as adhesion, migration, and signal transduction. By eliminating the expression of SDK1, these cell lines present a unique opportunity to explore the downstream effects on both physiological and pathological states.
The key mechanism of these cell lines lies in their ability to serve as a model for studying loss-of-function mutations, which provides insights into the gene’s involvement in various diseases, including cancer and tissue regeneration. Researchers can employ these knockout lines to analyze changes in cellular behavior, biochemical pathways, and molecular interactions, facilitating a deeper understanding of SDK1's biological significance.
In both research and clinical settings, SDK1 Gene Knockout Cell Lines offer considerable scientific importance as they enable the elucidation of gene function which is crucial for developing targeted therapies. By comparing these knockout cells with wild-type controls, researchers can assess fundamental biological processes, making them indispensable in the field of genetic research and drug discovery.
What sets our SDK1 Gene Knockout Cell Lines apart from alternative cell models is their high specificity and efficiency of the gene knockout achieved through advanced CRISPR technology, resulting in clear and reproducible phenotypic changes. Additionally, these cell lines are thoroughly validated to ensure consistent performance across experiments, offering reliability that is paramount in scientific research.
For researchers and clinicians aiming to investigate the implications of SDK1 in health and disease, the value of these cell lines is profound. They not only provide a robust platform for experimentation but also accelerate the translation of basic research findings into therapeutic strategies. Our company is dedicated to advancing biological research through high-quality products and services. With years of expertise in biotechnology, we ensure that our SDK1 Gene Knockout Cell Lines meet the highest standards of scientific rigor and reliability, empowering users to achieve groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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