Gene: SDC4
Official Full Name: syndecan 4provided by HGNC
Gene Summary: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04988 | SDC4 Knockout cell line (HeLa) | Human | SDC4 | 1:3~1:6 | Negative | Online Inquiry |
KO04989 | SDC4 Knockout cell line (HCT 116) | Human | SDC4 | 1:2~1:4 | Negative | Online Inquiry |
KO04990 | SDC4 Knockout cell line (HEK293) | Human | SDC4 | 1:3~1:6 | Negative | Online Inquiry |
KO04991 | SDC4 Knockout cell line (A549) | Human | SDC4 | 1:3~1:4 | Negative | Online Inquiry |
SDC4 Gene Knockout Cell Lines represent a specialized set of genetically engineered cell models in which the SDC4 gene, associated with cell signaling and adhesion, has been inactivated to study its biological roles. These cell lines provide invaluable tools for researchers aiming to dissect the functional implications of syndecan-4 (SDC4) in various physiological and pathological contexts, including cancer, wound healing, and tissue regeneration.
The primary function of SDC4 involves its role as a co-receptor that facilitates signal transduction pathways associated with growth factors and extracellular matrix components. By knocking out the SDC4 gene, researchers can elucidate its contribution to cell motility, proliferation, and apoptosis under specific conditions. The mechanisms associated with SDC4 highlight its importance in regulating cellular responses to environmental cues, making these knockout cell lines essential for exploring how disruptions in SDC4 signaling might lead to disease states, particularly in oncology.
In scientific research and clinical settings, SDC4 Gene Knockout Cell Lines are crucial for examining the roles of SDC4 in cancer progression and metastatic behavior, thus opening avenues for targeted therapies. Furthermore, they can serve as platforms for high-throughput drug screening, enhancing the efficiency of therapeutic development.
What sets our SDC4 Gene Knockout Cell Lines apart from alternative models is their robust validation and ease of use, along with the extensive characterization data provided to users. These lines are routinely characterized for phenotypic stability, ensuring that researchers obtain reliable and reproducible results.
Our commitment to scientific excellence drives us to deliver high-quality biological products that meet the evolving needs of researchers and clinicians. With expertise in genetic engineering and cell line development, our company stands at the forefront of advancing research capabilities, empowering scientists to unlock new discoveries in cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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