Gene: SARAF
Official Full Name: store-operated calcium entry associated regulatory factorprovided by HGNC
Gene Summary: Involved in regulation of store-operated calcium entry. Located in endoplasmic reticulum membrane and endoplasmic reticulum-plasma membrane contact site. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22291 | SARAF Knockout cell line (HeLa) | Human | SARAF | 1:3~1:6 | Negative | Online Inquiry |
KO22292 | SARAF Knockout cell line (HCT 116) | Human | SARAF | 1:2~1:4 | Negative | Online Inquiry |
KO22293 | SARAF Knockout cell line (HEK293) | Human | SARAF | 1:3~1:6 | Negative | Online Inquiry |
KO22294 | SARAF Knockout cell line (A549) | Human | SARAF | 1:3~1:4 | Negative | Online Inquiry |
SARAF Gene Knockout Cell Lines are a collection of genetically engineered cell lines designed specifically to facilitate the study of the SARAF (Store-Operated Calcium Entry-Associated Regulator) gene's functions and its implications in cellular signaling pathways. These cell lines feature a complete knockout of the SARAF gene, enabling researchers to investigate the gene's role in calcium homeostasis and its potential links to various diseases, including specific cancers and neurodegenerative disorders.
The key mechanism underlying these cell lines involves CRISPR-Cas9 technology, which ensures precise and effective disruption of the SARAF gene, allowing for the systematic analysis of altered phenotypes in physiological processes. By utilizing these knockout cell lines, researchers can assess the functional consequences of SARAF gene deletion, including effects on calcium signaling, apoptosis, and cellular proliferation. This enables in-depth exploration of molecular mechanisms and may lead to novel therapeutic insights.
Scientifically, SARAF Gene Knockout Cell Lines are invaluable in both research and clinical settings. They serve as essential tools for drug discovery, as they provide a platform to evaluate potential compounds targeting calcium regulation pathways. Moreover, these cell lines are crucial for understanding the genetic basis of diseases associated with dysregulated calcium signaling, ultimately contributing to the development of targeted therapeutic strategies.
Compared to alternative gene knockout systems, our SARAF Gene Knockout Cell Lines offer superior efficiency and specificity, minimizing off-target effects and providing researchers with consistent and reproducible results. Their versatility allows for a variety of experimental applications, including high-throughput screening, functional assays, and gene therapy research.
In summary, SARAF Gene Knockout Cell Lines present an essential resource for researchers and clinicians dedicated to elucidating the biochemical pathways influenced by the SARAF gene. Our commitment to precision and excellence in bioengineering ensures that these cell lines are backed by rigorous quality control and scientific validation, further enhancing their reliability and effectiveness as research tools.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.