Gene: SAMD13
Official Full Name: sterile alpha motif domain containing 13provided by HGNC
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23414 | SAMD13 Knockout cell line (HCT 116) | Human | SAMD13 | 1:2~1:4 | Negative | Online Inquiry |
KO23415 | SAMD13 Knockout cell line (HEK293) | Human | SAMD13 | 1:3~1:6 | Negative | Online Inquiry |
KO23416 | SAMD13 Knockout cell line (A549) | Human | SAMD13 | 1:3~1:4 | Negative | Online Inquiry |
SAMD13 Gene Knockout Cell Lines are genetically engineered cell lines created to specifically disrupt the expression of the SAMD13 gene, which encodes a protein involved in various cellular processes, including stress response and cellular metabolism. This product facilitates in-depth functional studies of SAMD13's role in both normal physiology and pathophysiological conditions, including cancer and neurodegenerative diseases.
The primary mechanism of action involves the usage of CRISPR-Cas9 technology, allowing precise alterations to the SAMD13 gene's sequence. This targeted gene disruption leads to the absence of the SAMD13 protein, enabling researchers to observe downstream effects on cellular signaling pathways, gene expression profiles, and metabolic activities. By studying these knockout models, scientists can gain insights into how modulation of SAMD13 influences cell growth, apoptosis, and response to environmental stressors.
Scientifically, SAMD13 gene knockout cell lines are critical tools for unraveling the complex biology of SAMD13 and its contributions to various diseases. These cell lines are particularly valuable in research settings focused on cancer biology, neurobiology, and metabolic disorders, providing a basis for potential therapeutic developments and targeted treatments.
Compared to conventional knockdown approaches, such as RNA interference, SAMD13 knockout cell lines offer permanent gene disruption, leading to more robust and reproducible results over time. This durability allows for long-term studies that are essential in elucidating the gene's function and the consequences of its loss in different contexts.
For researchers and clinicians alike, these cell lines represent a significant value in advancing scientific understanding and developing novel therapeutic strategies. The potential to derive new insights into disease mechanisms and therapeutic targets positions SAMD13 gene knockout cell lines as indispensable resources in molecular biology and translational research.
Our company has a proven track record in producing high-quality genetic models with unparalleled reliability and technical support. With cutting-edge technologies and rigorous quality control, we are committed to empowering researchers with the tools they need to advance their work in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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