Gene: SAMD12
Official Full Name: sterile alpha motif domain containing 12provided by HGNC
Gene Summary: Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasmic side of plasma membrane. Implicated in familial adult myoclonic epilepsy 1. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21358 | SAMD12 Knockout cell line (HeLa) | Human | SAMD12 | 1:3~1:6 | Negative | Online Inquiry |
KO21359 | SAMD12 Knockout cell line (HCT 116) | Human | SAMD12 | 1:2~1:4 | Negative | Online Inquiry |
KO21360 | SAMD12 Knockout cell line (HEK293) | Human | SAMD12 | 1:3~1:6 | Negative | Online Inquiry |
SAMD12 Gene Knockout Cell Lines are genetically engineered cell lines characterized by the targeted disruption of the SAMD12 gene, a significant player in various cellular processes, including cellular stress responses and metabolism. The knockout of this gene allows researchers to elucidate its function and role in different biological contexts, particularly in disease mechanisms.
These cell lines operate on a fundamental principle of genetic disruption, where the SAMD12 gene is intentionally rendered non-functional. This disruption is accomplished through advanced gene-editing technologies such as CRISPR-Cas9, which precisely alters the genomic sequence, allowing investigators to study the resultant phenotypic changes and observe the cellular pathways that are affected when SAMD12's functionality is lost.
The scientific importance of SAMD12 Gene Knockout Cell Lines lies in their application across various research fields, including cancer biology, metabolic disorders, and neurobiology. This tool enables sophisticated studies into the gene’s contributions to disease progression, potential biomarker identification, and therapeutic target exploration, ultimately advancing our understanding of the relevance of SAMD12 in maintaining cellular homeostasis and its involvement in pathological states.
What sets these cell lines apart from alternatives is their specificity and reliability. Researchers benefit from the knockout specificity that eliminates off-target effects common to less precise methods, allowing for reproducible and meaningful results. Furthermore, SAMD12 Gene Knockout Cell Lines are validated through extensive preliminary studies to ensure their functionality and applicability in various experimental designs.
For researchers and clinicians aiming to dissect intricate genetic interactions and cellular behaviors associated with the SAMD12 gene, these knockout models offer an invaluable asset in experimental setups. They facilitate a deeper investigation into gene function, pave the way for novel therapeutic insights, and foster greater innovation within the biomedical field.
By choosing SAMD12 Gene Knockout Cell Lines from our extensive portfolio, you are leveraging the expertise of our company, which focuses on delivering high-quality biological products tailored to the needs of the scientific community. Our commitment to innovation and reliability assures you of exceptional resources to support cutting-edge research efforts.
Please note that all services are for research use only. Not intended for any clinical use.
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