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SALL2 Knockout Cell Lines

Gene: SALL2

Official Full Name: spalt like transcription factor 2provided by HGNC

Gene Summary: This gene encodes a protein containing multiple zinc finger domains. The encoded protein functions in optical fissure closure during development of the eye in the embryo. Mutations in this gene are associated with ocular coloboma. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35528 SALL2 Knockout cell line (HeLa) Human SALL2 1:3~1:6 Negative Online Inquiry
KO35529 SALL2 Knockout cell line (HEK293) Human SALL2 1:3~1:6 Negative Online Inquiry
KO35530 SALL2 Knockout cell line (A549) Human SALL2 1:3~1:4 Negative Online Inquiry

Background

SALL2 Gene Knockout Cell Lines are specialized cell lines designed to lack the SALL2 gene, which encodes for a transcription factor involved in developmental processes and cell differentiation. These cell lines are constructed using advanced CRISPR/Cas9 gene-editing technology, ensuring precise and efficient knockout of the SALL2 gene. The absence of SALL2 allows researchers to study its functional implications in various biological pathways, offering insights into cellular behavior, gene regulation, and developmental biology.

The key function of SALL2 Gene Knockout Cell Lines is to serve as a robust model for analyzing the role of the SALL2 gene in health and disease. By comparing these knockout lines to their wild-type counterparts, researchers can elucidate the gene's contributions to cellular processes such as proliferation, apoptosis, and differentiation. Additionally, the knockout cell lines provide an invaluable tool for investigating the potential involvement of SALL2 in cancer progression and other pathologies associated with aberrant gene regulation.

The scientific importance of these cell lines extends to various applications in both basic research and clinical settings. For instance, they are essential for drug screening assays, genetic studies, and the exploration of gene therapy strategies targeting SALL2-related disorders. The ability to directly manipulate and study the SALL2 gene's effects mirrors the complexities found in vivo, thereby enhancing translational research efforts.

One of the significant advantages of SALL2 Gene Knockout Cell Lines lies in their specificity and reliability compared to other genetic models. Unlike transient knockdown strategies, these stable knockout lines provide consistent and reproducible results, eliminating variability that may arise from temporary gene silencing techniques. This stability is particularly beneficial when conducting long-term experiments or studying rare cellular phenotypes.

For researchers and clinicians dedicated to understanding the intricacies of gene function in development and disease, SALL2 Gene Knockout Cell Lines represent a valuable resource. Their ability to dissect the role of SALL2 in a controlled manner allows for the development of targeted therapeutic approaches, underlining their relevance in both academic and clinical research contexts.

Our company specializes in the development of high-quality genetic tools, providing researchers with the means to advance their studies through innovative solutions like SALL2 Gene Knockout Cell Lines. By leveraging cutting-edge gene-editing technologies and rigorous quality control, we ensure that our products meet the highest standards needed for impactful scientific research.

Please note that all services are for research use only. Not intended for any clinical use.

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