Gene: SAFB2
Official Full Name: scaffold attachment factor B2provided by HGNC
Gene Summary: The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. [provided by RefSeq, May 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32946 | SAFB2 Knockout cell line (HeLa) | Human | SAFB2 | 1:3~1:6 | Negative | Online Inquiry |
KO32947 | SAFB2 Knockout cell line (HCT 116) | Human | SAFB2 | 1:2~1:4 | Negative | Online Inquiry |
KO32948 | SAFB2 Knockout cell line (HEK293) | Human | SAFB2 | 1:3~1:6 | Negative | Online Inquiry |
KO32949 | SAFB2 Knockout cell line (A549) | Human | SAFB2 | 1:3~1:4 | Negative | Online Inquiry |
SAFB2 Gene Knockout Cell Lines represent a cutting-edge biological research tool initiated through the precise disruption of the SAFB2 gene, known for its roles in gene regulation and cellular processes. These cell lines are engineered using CRISPR/Cas9 technology, resulting in a complete knockout of SAFB2 expression. This targeted gene disruption allows for the in-depth study of SAFB2's function in various biological contexts, including its implications in cellular growth, differentiation, and responses to stress.
The primary mechanism through which SAFB2 influences cellular dynamics is its involvement in the regulation of gene expression, particularly through interactions with transcription factors and RNA processing. By utilizing SAFB2 Gene Knockout Cell Lines, researchers can elucidate the pathways and molecular mechanisms dependent on SAFB2, paving the way for novel insights into oncogenesis, developmental biology, and therapeutic resistance. The applicability of these cell lines extends beyond basic research, holding promise in drug discovery and the development of gene therapies targeting related pathologies.
This product stands out from conventional knockout models by offering superior specificity and efficiency in gene editing, as well as the potential for enhanced reproducibility in experimental results. SAFB2 Gene Knockout Cell Lines enable researchers to obtain clearer, unambiguous data, enabling more consistent and validated findings compared to less refined alternatives.
For scientists and clinicians looking to deepen their understanding of SAFB2's multifaceted roles, these cell lines represent a valuable resource. Their use can help support the next generation of research, unlocking novel therapeutic approaches to complex diseases. Our company boasts extensive expertise in genetic engineering and has developed a comprehensive portfolio of tools tailored to advancing biological research. We are committed to providing high-quality products that contribute to groundbreaking discoveries in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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