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S100A16 Knockout Cell Lines

Gene: S100A16

Official Full Name: S100 calcium binding protein A16provided by HGNC

Gene Summary: Enables calcium ion binding activity and protein homodimerization activity. Predicted to act upstream of or within response to calcium ion. Located in several cellular components, including cytosol; extracellular space; and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25582 S100A16 Knockout cell line (HeLa) Human S100A16 1:3~1:6 Negative Online Inquiry
KO25583 S100A16 Knockout cell line (HCT 116) Human S100A16 1:2~1:4 Negative Online Inquiry
KO25584 S100A16 Knockout cell line (A549) Human S100A16 1:3~1:4 Negative Online Inquiry

Background

S100A16 Gene Knockout Cell Lines are engineered cellular models that have undergone precise CRISPR-Cas9 gene editing to disrupt the expression of the S100A16 gene, which encodes a member of the S100 protein family involved in calcium binding and significant signaling pathways. By eliminating S100A16 expression, these cell lines facilitate the study of its role in various physiological and pathological processes, including inflammation, cancer, and cellular differentiation.

The key functionality of these knockout cell lines lies in their ability to serve as a tool for dissecting the specific contributions of S100A16 in cellular environments. Researchers can utilize these models to explore the aberrations associated with S100A16 deficiency, enabling insights into its impact on processes such as apoptosis, cell proliferation, and immune response regulation. By generating a reliable system where S100A16 is absent, experimental outcomes can be more clearly correlated with this protein's presence or absence, thereby delineating its functional significance within both basic and applied biological research.

Scientific interest in S100A16 pertains to its emerging roles in various clinical conditions, including its implications in tumor progression and inflammatory diseases. These knockout cell lines offer a valuable resource for identifying potential therapeutic targets and validating novel drugs that may modulate S100A16 expression or activity.

Compared to traditional methods such as knockdown techniques, S100A16 Gene Knockout Cell Lines provide a complete loss-of-function approach, yielding more clear-cut and reproducible data. This ensures that the biological responses observed are directly attributable to the absence of the S100A16 protein, rather than residual activities that may occur with subtler gene silencing methods.

For researchers and clinicians striving to uncover mechanisms underlying disease processes and evaluate new therapeutic avenues, S100A16 Gene Knockout Cell Lines deliver precision, reliability, and comprehensive applicability. Their creation is backed by our company's extensive experience and expertise in gene editing technologies and model organism development, making them an ideal choice for advancing your research or clinical inquiries in the biomedical field.

Please note that all services are for research use only. Not intended for any clinical use.

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