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RTN4RL1 Knockout Cell Lines

Gene: RTN4RL1

Official Full Name: reticulon 4 receptor like 1provided by HGNC

Gene Summary: Enables signaling receptor activity. Predicted to be involved in negative regulation of axon regeneration. Located in cell surface and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23965 RTN4RL1 Knockout cell line (HCT 116) Human RTN4RL1 1:2~1:4 Negative Online Inquiry
KO23966 RTN4RL1 Knockout cell line (HEK293) Human RTN4RL1 1:3~1:6 Negative Online Inquiry
KO23967 RTN4RL1 Knockout cell line (A549) Human RTN4RL1 1:3~1:4 Negative Online Inquiry

Background

RTN4RL1 Gene Knockout Cell Lines represent a cutting-edge research tool designed for studying the specific biological functions and roles of the RTN4RL1 gene, which encodes a protein involved in neuronal signaling and axon regeneration. These cell lines have been meticulously engineered to create a complete knockout of the RTN4RL1 gene, allowing researchers to investigate the gene's contributions to essential cellular processes such as neurodevelopment, synaptic plasticity, and response to injury.

The primary function of the RTN4RL1 knockout cell lines is to enable in-depth analysis of the cellular and molecular mechanisms mediated by this gene. By eliminating the gene's expression, scientists can evaluate the resulting phenotypic and functional changes, providing insights into the pathways regulated by RTN4RL1 and its potential involvement in neurodegenerative diseases and traumatic nerve injuries. Researchers can leverage these models to elucidate critical signaling cascades, identify novel therapeutic targets, and test the efficacy of potential interventions.

From a scientific perspective, the RTN4RL1 Gene Knockout Cell Lines hold immense value in both research and clinical settings. They facilitate a clearer understanding of neuronal behavior in vitro, offering a reliable system for drug screening and cellular assays. The precise gene editing technology used in generating these cell lines ensures high specificity and reproducibility, making them a preferred choice for researchers aiming for consistent results.

Compared to alternative gene editing methods, the RTN4RL1 knockout models offer significant advantages, including ease of use, reduced off-target effects, and robust characterization to confirm successful gene disruption. Additionally, their availability can accelerate research timelines, leading to faster advancements in understanding the gene's role in health and disease.

Researchers, clinicians, and biotechnology companies will find these knockout cell lines invaluable due to their potential to unravel complex biological questions and translate findings into clinical applications. By providing tools that enable comprehensive investigations into neurobiology, we are committed to fostering innovation and discovery in this critical area of research.

As a leader in the development of specialized biological products, our company prides itself on delivering high-quality, precisely engineered cell lines that empower researchers to advance their scientific endeavors and translate findings into real-world solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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