Gene: RPH3A
Official Full Name: rabphilin 3Aprovided by HGNC
Gene Summary: The protein encoded by this gene is thought to be an effector for RAB3A, which is a small G protein that acts in the late stages of neurotransmitter exocytosis. The encoded protein may be involved in neurotransmitter release and synaptic vesicle traffic. [provided by RefSeq, Dec 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30188 | RPH3A Knockout cell line (HEK293) | Human | RPH3A | 1:3~1:6 | Negative | Online Inquiry |
RPH3A Gene Knockout Cell Lines are genetically modified cell lines in which the RPH3A gene has been specifically disrupted, enabling researchers to study the role of this gene in various biological processes. The RPH3A gene encodes a protein implicated in neurotransmitter vesicle trafficking, playing a crucial role in synaptic transmission and cellular signaling. By utilizing these knockout cell lines, researchers can investigate the cellular mechanisms that underpin neurodegenerative diseases, synaptic disorders, and other pathologies associated with impaired vesicle dynamics.
The key function of RPH3A Gene Knockout Cell Lines lies in their ability to provide a controlled environment for the examination of gene function and interaction. The knockout enables the observation of phenotypic changes and alterations in signaling pathways resulting from the absence of RPH3A. Molecular techniques, including CRISPR-Cas9 gene editing, have facilitated the development of these cell lines, ensuring precision and reproducibility in experiments. This product allows for detailed studies on the effects of RPH3A deficiency in transgenic models, promoting an enhanced understanding of its clinical relevance.
In research and clinical settings, RPH3A Gene Knockout Cell Lines serve as invaluable tools in drug discovery and the elucidation of therapeutic targets. Their application extends to neurobiology, pharmacology, and genetic research, positioning them as essential resources for advancing our understanding of complex diseases. Compared to other genetic models, these knockout cell lines offer high specificity and targeted disruption, minimizing off-target effects often encountered with earlier genetic manipulation techniques.
The value of RPH3A Gene Knockout Cell Lines lies in their potential to accelerate the discovery of novel therapeutic interventions and biomarkers for neurodegenerative conditions. Researchers and clinicians can leverage these cell lines to refine their hypotheses, validate findings, and foster innovation in translational medicine. Our company is dedicated to delivering high-quality biological products, backed by extensive scientific expertise and a commitment to advancing research in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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