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ROGDI Knockout Cell Lines

Gene: ROGDI

Official Full Name: rogdi atypical leucine zipperprovided by HGNC

Gene Summary: Involved in brain development; neurogenesis; and odontogenesis of dentin-containing tooth. Located in nuclear envelope. Implicated in Kohlschutter-Tonz syndrome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14433 ROGDI Knockout cell line (HeLa) Human ROGDI 1:3~1:6 Negative Online Inquiry
KO14434 ROGDI Knockout cell line (HCT 116) Human ROGDI 1:2~1:4 Negative Online Inquiry
KO14435 ROGDI Knockout cell line (HEK293) Human ROGDI 1:3~1:6 Negative Online Inquiry
KO14436 ROGDI Knockout cell line (A549) Human ROGDI 1:3~1:4 Negative Online Inquiry

Background

ROGDI Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to disrupt the ROGDI gene, a component implicated in various biological processes and disease states. These cell lines serve as essential tools for researchers studying gene function, cellular signaling, and therapeutic targets in conditions such as neurodegeneration and cancer.

The key function of ROGDI Gene Knockout Cell Lines lies in their ability to facilitate the investigation of the ROGDI gene's role in cellular mechanisms. By employing CRISPR-Cas9 gene-editing technology, these cell lines allow for the precise knockout of the ROGDI gene, enabling researchers to observe the downstream effects of its absence on cellular behavior, proliferation, and response to stimuli. Such insights are crucial for understanding the complexities of gene interactions and identifying potential pathways for targeted interventions.

In terms of scientific importance, ROGDI Gene Knockout Cell Lines are invaluable in both research and clinical settings. They serve as platforms for drug screening, biomarker discovery, and validation of therapeutic strategies aimed at correcting pathogenic gene functions. By elucidating the role of ROGDI in disease mechanisms, these cell lines can significantly contribute to the development of novel treatments and improve diagnostic tools.

Unlike conventional methods of gene knockout, ROGDI Gene Knockout Cell Lines present unique advantages, including high specificity, reproducibility, and ease of use in various experimental setups. Their established protocols and consistent performance eliminate the variability associated with non-targeted gene disruption approaches. Additionally, researchers benefit from well-characterized genetic backgrounds that can be tailored to specific experimental needs.

The value of ROGDI Gene Knockout Cell Lines to researchers and clinicians lies in their ability to accelerate the understanding of complex biological systems and disease mechanisms, ultimately transforming scientific knowledge into practical therapies. These advanced cellular models empower users to uncover detailed biological insights, making them essential assets in the laboratory.

Our company is committed to offering state-of-the-art biological products backed by a strong foundation in genetic engineering and cellular biology. With an emphasis on quality and innovation, we provide researchers with the tools they need to advance their studies and achieve meaningful results in understanding gene function.

Please note that all services are for research use only. Not intended for any clinical use.

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