Home / ROBO2 Knockout Cell Lines

ROBO2 Knockout Cell Lines

Gene: ROBO2

Official Full Name: roundabout guidance receptor 2provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07275 ROBO2 Knockout cell line (HeLa) Human ROBO2 1:3~1:6 Negative Online Inquiry
KO07276 ROBO2 Knockout cell line (HEK293) Human ROBO2 1:3~1:6 Negative Online Inquiry

Background

ROBO2 Gene Knockout Cell Lines are a specialized biological research product designed to facilitate the exploration of the roles and pathways associated with the ROBO2 gene. This gene encodes a member of the roundabout receptor family, which is critically involved in axon guidance and neural development. By utilizing CRISPR/Cas9 gene-editing technology, these knockout cell lines have been meticulously engineered to deliver a complete loss of function for the ROBO2 gene, allowing researchers to investigate its biological implications with unprecedented precision.

The primary function of these cell lines is to enable the study of ROBO2’s impact on cellular behavior, signaling pathways, and developmental processes. By examining cellular responses in the absence of ROBO2, scientists can elucidate its role in various physiological and pathological contexts, such as neuronal regeneration, cancer metastasis, and cardiovascular development. These insights are crucial for advancing the understanding of disorders associated with aberrant ROBO2 signaling.

The scientific importance of ROBO2 Gene Knockout Cell Lines cannot be overstated; they serve as vital tools for both fundamental research and translational applications. In research settings, they are invaluable for developing novel therapeutic strategies and identifying potential drug targets. Moreover, in clinical contexts, understanding ROBO2's functions may yield innovative interventions for diseases where its dysregulation is implicated.

One of the standout advantages of these knockout cell lines is their convenience and reliability compared to alternative models, such as traditional gene silencing techniques or whole organism studies, which often present challenges in scalability and reproducibility. ROBO2 Gene Knockout Cell Lines provide a stable and consistent platform for investigation, streamlining workflows and accelerating research timelines.

Additionally, our commitment to quality assurance and extensive characterization ensures that researchers receive high-fidelity products tailored to their experimental needs. Our expertise in genetics and cell line development positions us as a leader in providing innovative biological tools. By incorporating ROBO2 Gene Knockout Cell Lines into your research arsenal, you empower your studies with a powerful resource, driving forward the discovery of new avenues for therapeutic intervention.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.