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RNPEP Knockout Cell Lines

Gene: RNPEP

Official Full Name: arginyl aminopeptidaseprovided by HGNC

Gene Summary: Predicted to enable metalloaminopeptidase activity. Predicted to be involved in proteolysis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35600 RNPEP Knockout cell line (HeLa) Human RNPEP 1:3~1:6 Negative Online Inquiry
KO35601 RNPEP Knockout cell line (HCT 116) Human RNPEP 1:2~1:4 Negative Online Inquiry
KO35602 RNPEP Knockout cell line (HEK293) Human RNPEP 1:3~1:6 Negative Online Inquiry
KO35603 RNPEP Knockout cell line (A549) Human RNPEP 1:3~1:4 Negative Online Inquiry

Background

RNPEP Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate the study of the RNPEP gene, which encodes for the enzyme renal dipeptidase. This product involves the targeted disruption of the RNPEP gene through CRISPR-Cas9 technology, enabling researchers to create models that lack the functional protein. By employing precise gene-editing techniques, these cell lines are invaluable for investigating the biological roles of RNPEP in various physiological processes, including amino acid metabolism and the regulation of blood pressure.

The primary function of RNPEP Gene Knockout Cell Lines lies in their ability to support research that elucidates the metabolic pathways involving renal dipeptidase. The cells display altered metabolic profiles, allowing for unique insights into the implications of kidney function, hypertension, and cardiovascular health. Moreover, these knockout models are essential for pharmacological studies, toxicity assessments, and drug development processes aimed at targeting renal-related disorders.

The scientific importance of these cell lines extends into both research and clinical settings. Their applications range from fundamental studies in molecular biology to advanced translational research aimed at developing therapeutic strategies for renal diseases. The ability to create specific gene knockouts accelerates the discovery of gene functions and pathological mechanisms, which is critical for advancing personalized medicine.

In contrast to traditional knockout models, RNPEP Gene Knockout Cell Lines utilize cutting-edge CRISPR technology, offering higher specificity and efficiency in gene editing. This precision reduces off-target effects and enhances the reliability of experimental outcomes. Researchers benefit from a more streamlined and reproducible approach, leading to time and cost-effective study designs.

Moreover, these cell lines are backed by extensive validation and characterization, ensuring robust performance in a variety of experimental conditions. For researchers and clinicians who aim for quality and reliability in their studies, RNPEP Gene Knockout Cell Lines stand out as an essential tool.

Our company is committed to providing high-quality biological products that support innovative research and clinical advancements. Leveraging our expertise in genetic engineering and cell line development, we empower scientists to explore new horizons in biological research effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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