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RNF41 Knockout Cell Lines

Gene: RNF41

Official Full Name: ring finger protein 41provided by HGNC

Gene Summary: This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06568 RNF41 Knockout cell line (HeLa) Human RNF41 1:3~1:6 Negative Online Inquiry
KO06569 RNF41 Knockout cell line (HCT 116) Human RNF41 1:2~1:4 Negative Online Inquiry
KO06570 RNF41 Knockout cell line (HEK293) Human RNF41 1:3~1:6 Negative Online Inquiry
KO06571 RNF41 Knockout cell line (A549) Human RNF41 1:3~1:4 Negative Online Inquiry

Background

RNF41 Gene Knockout Cell Lines are genetically engineered cell cultures specifically designed to lack the RNF41 gene, which encodes an E3 ubiquitin ligase involved in regulating protein degradation. These knockout cell lines serve as invaluable tools for researchers investigating the functional roles of RNF41 in cellular processes such as protein homeostasis, signal transduction, and immune response. The mechanism of action of these cell lines lies in their ability to provide a controlled environment in which the influence of RNF41 can be examined, facilitating the study of its roles in the ubiquitin-proteasome system.

The scientific importance of RNF41 Gene Knockout Cell Lines extends to various applications in both fundamental research and clinical settings. By utilizing these cell lines, scientists can elucidate the pathways regulated by RNF41, investigate its contributions to diseases such as cancer and neurodegeneration, and explore its potential as a therapeutic target. This product is particularly valuable for researchers studying the complexities of protein modification and signal transduction, as it allows for rigorous investigation without the confounding effects of RNF41.

One of the primary advantages of RNF41 Gene Knockout Cell Lines is their specificity; unlike other genetic manipulation techniques, these knockout lines eliminate the gene entirely, ensuring a clear understanding of its functions. Compared to alternative methods like RNA interference (RNAi), which may yield partial knockdown effects, these knockout lines provide a more comprehensive approach for studying the role of RNF41.

Moreover, the ease of integration into existing research workflows makes these cell lines an attractive option for both established researchers and newcomers to cellular biology. The value of RNF41 Gene Knockout Cell Lines lies not only in their ability to simplify experimental design but also in their contribution to advancing our understanding of critical biological processes. Our company, with its commitment to producing high-quality, innovative genetic tools, offers expertise in providing tailored solutions that empower researchers in their quest for discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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