Gene: RNF38
Official Full Name: ring finger protein 38provided by HGNC
Gene Summary: This gene encodes a protein with a coiled-coil motif and a RING-H2 motif (C3H2C2) at its carboxy-terminus. The RING motif is a zinc-binding domain found in a large set of proteins playing roles in diverse cellular processes including oncogenesis, development, signal transduction, and apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21898 | RNF38 Knockout cell line (HeLa) | Human | RNF38 | 1:3~1:6 | Negative | Online Inquiry |
KO21899 | RNF38 Knockout cell line (HCT 116) | Human | RNF38 | 1:2~1:4 | Negative | Online Inquiry |
KO21900 | RNF38 Knockout cell line (HEK293) | Human | RNF38 | 1:3~1:6 | Negative | Online Inquiry |
KO21901 | RNF38 Knockout cell line (A549) | Human | RNF38 | 1:3~1:4 | Negative | Online Inquiry |
RNF38 Gene Knockout Cell Lines are genetically modified cell lines where the RNF38 gene has been inactivated or "knocked out." This innovative biological tool is pivotal in understanding the functional role of the RNF38 protein, which is implicated in various cellular processes including protein ubiquitination and regulation of gene expression.
These cell lines operate through the disruption of the RNF38 gene via CRISPR-Cas9 technology or other gene-editing methodologies, allowing researchers to study the resultant phenotypic changes. By observing these alterations, scientists can gain valuable insights into the pathophysiological effects caused by RNF38 deficiency, contributing to broader understandings of diseases such as cancer and neurodegenerative disorders.
Scientifically, RNF38 Gene Knockout Cell Lines are invaluable for both fundamental and applied research. They serve as powerful models for investigating the mechanisms of ubiquitin-mediated protein degradation and signal transduction pathways. In clinical settings, these models can aid in drug discovery, therapeutic target validation, and the study of drug resistance mechanisms, potentially leading to more effective treatment strategies.
What sets RNF38 Gene Knockout Cell Lines apart from other genetically modified cell lines is their specificity and efficiency in targeting the RNF38 gene, coupled with rigorous validation to ensure reproducibility and reliability in experimental outcomes. This precision reduces the likelihood of off-target effects, leading to clearer experimental interpretations.
For researchers and clinicians invested in decoding the complexities of cellular function and disease mechanisms, RNF38 Gene Knockout Cell Lines present a crucial resource that drives innovation and discovery. Our company, renowned for its commitment to advancing biological research, offers these specialized cell lines, backed by extensive expertise in genetic modification and cell biology. Harness the power of precision biology with RNF38 Gene Knockout Cell Lines and propel your research to new heights.
Please note that all services are for research use only. Not intended for any clinical use.
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