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RNF215 Knockout Cell Lines

Gene: RNF215

Official Full Name: ring finger protein 215provided by HGNC

Gene Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38224 RNF215 Knockout cell line (HeLa) Human RNF215 1:3~1:6 Negative Online Inquiry
KO38225 RNF215 Knockout cell line (HCT 116) Human RNF215 1:2~1:4 Negative Online Inquiry
KO38226 RNF215 Knockout cell line (HEK293) Human RNF215 1:3~1:6 Negative Online Inquiry
KO38227 RNF215 Knockout cell line (A549) Human RNF215 1:3~1:4 Negative Online Inquiry

Background

RNF215 Gene Knockout Cell Lines are specialized cellular models where the RNF215 gene has been inactivated through the use of CRISPR/Cas9 technology. This gene encodes a protein implicated in various cellular processes, including DNA repair, cell cycle regulation, and cellular response to stress. By creating knockout cell lines, researchers can investigate the specific role of RNF215 in these biological functions, helping to elucidate pathways that may contribute to conditions such as cancer.

The primary mechanism of the RNF215 knockout involves the targeted disruption of the gene, which leads to the absence of the encoded protein. This allows researchers to study the consequent effects on cellular behavior, gene expression, and signaling pathways in a controlled environment. These cell lines can serve as a crucial tool for exploring gene function, drug interactions, and potential therapeutic targets, making them invaluable in both basic and translational research.

The scientific importance of RNF215 knockout cell lines is underscored by their applications in cancer research, pharmacology, and genetic studies. By examining how the absence of RNF215 influences cell proliferation, apoptosis, or resistance to chemotherapeutics, researchers can identify novel biomarkers or therapeutic strategies that may improve patient outcomes in oncology.

One of the key advantages of using RNF215 knockouts is the precision and efficiency facilitated by the CRISPR technology employed in their generation. Compared to conventional methods such as RNA interference, gene knockout approaches offer a more robust and long-lasting alteration of gene function without the variability associated with transient knockdown. Additionally, these cell lines are ready to use and extensively characterized, ensuring reliability and reproducibility in experimental results.

For researchers and clinicians, the RNF215 Gene Knockout Cell Lines represent a powerful tool for advancing the understanding of complex biological systems and the development of new therapeutic approaches. Utilizing these lines opens up avenues for innovative studies that can lead to impactful discoveries.

Our company specializes in the production of high-quality, genetically modified cell lines and leverages cutting-edge technologies to meet the evolving needs of the scientific community. With a commitment to excellence, we provide robust biological products, such as the RNF215 Gene Knockout Cell Lines, to empower researchers and facilitate groundbreaking scientific advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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