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RNF212 Knockout Cell Lines

Gene: RNF212

Official Full Name: ring finger protein 212provided by HGNC

Gene Summary: This gene encodes a RING finger protein that may function as a ubiquitin ligase. The encoded protein may be involved in meiotic recombination. This gene is located within a linkage disequilibrium block and polymorphisms in this gene may influence recombination rates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14455 RNF212 Knockout cell line (HeLa) Human RNF212 1:3~1:6 Negative Online Inquiry
KO14456 RNF212 Knockout cell line (A549) Human RNF212 1:3~1:4 Negative Online Inquiry

Background

RNF212 Gene Knockout Cell Lines are meticulously developed cellular models designed to facilitate the study of the RNF212 gene, a critical component implicated in various biological processes and disease mechanisms. Through targeted gene editing techniques, these cell lines are rendered deficient in RNF212 expression, thereby allowing researchers to investigate the resultant phenotypic and molecular variations. This knockout approach enables an in-depth analysis of RNF212’s roles in cellular pathways, DNA damage response, and potential interactions with other genes relevant to cancer biology and genomic stability.

The key mechanism underlying the functionality of RNF212 Gene Knockout Cell Lines resides in the CRISPR-Cas9 gene editing technology that efficiently disrupts the specific genomic sequence of RNF212. By producing a loss-of-function scenario, researchers can explore alterations in signaling pathways and cellular behavior attributable to the absence of RNF212. This can lead to a greater understanding of its contribution to pathophysiology, especially in the context of tumorigenesis or therapeutic resistance.

The scientific importance of these knockout cell lines extends beyond basic research; they are pivotal for drug discovery, biomarker identification, and validation of therapeutic targets. In clinical settings, understanding the RNF212 gene’s function may unveil novel intervention strategies against diseases characterized by dysregulated gene expression.

Compared to traditional models such as wild-type cell lines or less precise gene editing methods, RNF212 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility, significantly enhancing experimental reliability. Their rigorous validation ensures users a consistent platform for hypothesis-driven research.

For researchers and clinicians aiming to unravel the complexities of genetic influence on health and disease, these cell lines present a valuable tool, providing insights at both genetic and phenotypic levels. Our company, with its expertise in advanced genetic engineering technologies, is committed to delivering high-quality and innovative biological products that empower the scientific community. By choosing RNF212 Gene Knockout Cell Lines, you are equipping your research with a superior model that can lead to groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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