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RNF19B Knockout Cell Lines

Gene: RNF19B

Official Full Name: ring finger protein 19Bprovided by HGNC

Gene Summary: This gene encodes a multi-pass membrane protein containing two RING-type and one IBR-type zinc finger motifs. The encoded protin is an E3 ubiquitin-protein ligase that plays a role in the cytotoxic effects of natural killer (NK) cells. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes X and Y in a possible pseudoautosomal region. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27025 RNF19B Knockout cell line (HeLa) Human RNF19B 1:3~1:6 Negative Online Inquiry
KO27026 RNF19B Knockout cell line (HCT 116) Human RNF19B 1:2~1:4 Negative Online Inquiry
KO27027 RNF19B Knockout cell line (HEK293) Human RNF19B 1:3~1:6 Negative Online Inquiry
KO27028 RNF19B Knockout cell line (A549) Human RNF19B 1:3~1:4 Negative Online Inquiry

Background

RNF19B Gene Knockout Cell Lines are specialized cell lines that have been genetically engineered to lack the expression of the RNF19B gene, a critical regulator involved in various cellular processes, including ubiquitination pathways and transcriptional regulation. This innovative tool allows researchers to investigate the biological roles of RNF19B in cellular mechanisms such as signal transduction, protein degradation, and gene expression modulation.

The primary function of RNF19B Gene Knockout Cell Lines is to serve as a model for understanding the consequences of RNF19B loss on cellular behavior. Without the activity of RNF19B, these cell lines exhibit altered pathways, providing insight into cellular homeostasis and disease mechanisms. Researchers can utilize these cell lines to study the functional relevance of RNF19B in cancer biology, neurodegenerative disorders, and other conditions where dysfunctional protein degradation pathways are implicated.

The scientific importance of these cell lines lies in their application in basic and applied research settings. They facilitate the creation of hypothesis-driven experiments aimed at elucidating gene function, validating potential drug targets, and exploring therapeutic interventions. Moreover, these cell lines can be utilized in high-throughput screening assays, enabling the identification of compounds that alter cellular responses specific to the RNF19B pathway.

Among the advantages of RNF19B Gene Knockout Cell Lines compared to alternatives is the specificity of gene knockout, which allows researchers to eliminate the confounding effects of other genes while studying RNF19B's role. Additionally, these cell lines are available in various backgrounds, enhancing their compatibility with a wide range of experimental designs.

For researchers and clinicians focused on unraveling the complexities of gene function and its implications in health and disease, RNF19B Gene Knockout Cell Lines are an invaluable resource. The elimination of RNF19B provides a clear window into its contributions to critical biological processes, thus empowering scientists to make groundbreaking discoveries.

Our company, a leader in the field of genetic engineering and biological research products, is committed to providing high-quality, reliable tools like RNF19B Gene Knockout Cell Lines to support the ever-evolving needs of the scientific community. We leverage cutting-edge technologies and extensive expertise to ensure our products drive innovation in research and clinical settings.

Please note that all services are for research use only. Not intended for any clinical use.

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