Gene: RNF166
Official Full Name: ring finger protein 166provided by HGNC
Gene Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30565 | RNF166 Knockout cell line (HeLa) | Human | RNF166 | 1:3~1:6 | Negative | Online Inquiry |
KO30566 | RNF166 Knockout cell line (HCT 116) | Human | RNF166 | 1:2~1:4 | Negative | Online Inquiry |
KO30567 | RNF166 Knockout cell line (HEK293) | Human | RNF166 | 1:3~1:6 | Negative | Online Inquiry |
KO30568 | RNF166 Knockout cell line (A549) | Human | RNF166 | 1:3~1:4 | Negative | Online Inquiry |
RNF166 Gene Knockout Cell Lines are specialized cell lines engineered to lack the RNF166 gene, a key component in various cellular pathways including ubiquitination and protein homeostasis. These knockout models serve as powerful tools for understanding the functional role of the RNF166 gene in cellular processes and disease mechanisms. By systematically removing the influence of this gene, researchers gain insights into how its absence can affect cellular growth, differentiation, and response to stressors or therapeutic agents.
The primary function of RNF166 involves its role in modulating the ubiquitin-proteasome system, which is critical for protein degradation and turnover. Without RNF166, cells may exhibit altered protein stability, leading to the accumulation of misfolded proteins or dysregulated signaling pathways. This mechanism can be exploited in various research contexts, particularly in studies related to cancer biology, neurodegenerative disorders, and metabolic diseases, where the RNF166 gene may play a pivotal role.
In a clinical setting, these cell lines provide an invaluable resource for drug discovery and the identification of therapeutic targets. Their unique genetic background allows for the exploration of how specific inhibitors or molecular agents can restore normal cellular functions, making it possible to investigate potential treatments for diseases linked to RNF166 dysfunction.
Compared to traditional models, RNF166 Gene Knockout Cell Lines offer distinct advantages such as higher specificity and reproducibility in experimental outcomes. Existing alternatives may produce variability due to the presence of multiple compensatory pathways. Thus, utilizing our knockout cell lines can lead to more precise data and reliable translational insights.
Ultimately, RNF166 Gene Knockout Cell Lines are indispensable for researchers and clinicians seeking to unravel the complexities of gene function and disease pathology. Our company is committed to providing high-quality biological products that empower scientific advancement, backed by our extensive expertise in cell line development and gene editing technologies. By choosing our products, you are investing in exceptional research tools designed to enhance the efficiency and efficacy of your scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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