Gene: RNF157
Official Full Name: ring finger protein 157provided by HGNC
Gene Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in negative regulation of apoptotic process; positive regulation of dendrite extension; and protein ubiquitination. Predicted to be located in cell body. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30746 | RNF157 Knockout cell line (HeLa) | Human | RNF157 | 1:3~1:6 | Negative | Online Inquiry |
KO30747 | RNF157 Knockout cell line (HEK293) | Human | RNF157 | 1:3~1:6 | Negative | Online Inquiry |
KO30748 | RNF157 Knockout cell line (A549) | Human | RNF157 | 1:3~1:4 | Negative | Online Inquiry |
RNF157 Gene Knockout Cell Lines are specialized genetically modified cell lines designed for the functional characterization of the RNF157 gene, a member of the RING finger E3 ubiquitin ligase family. These cell lines have been engineered to completely eliminate the expression of RNF157, enabling researchers to study its biological roles and implications in cellular processes. By creating a precise disruption in the RNF157 gene, these knockout models facilitate investigations into the associated pathways and regulatory mechanisms, expanding our understanding of cellular signaling and protein homeostasis.
The key mechanism behind the functionality of RNF157 Gene Knockout Cell Lines relies on CRISPR-Cas9 technology or similar gene-editing techniques, which allows for specific and efficient gene disruption. The absence of RNF157 provides a unique platform to explore its role in cellular responses, including stress responses, proliferation, and apoptosis. Moreover, these knockout cell lines serve as critical tools in drug discovery, offering insights into the potential therapeutic targeting of RNF157-related pathways in various diseases, including cancer.
In scientific research and clinical settings, the RNF157 knockout models hold significant importance for elucidating gene function, studying disease mechanisms, and screening new therapeutic agents. Compared to traditional methods of gene silencing, such as RNA interference, the knockout approach yields more definitive insights regarding the biological role of the gene, as it allows for the complete abrogation of its function rather than transient suppression.
The unique selling points of RNF157 Gene Knockout Cell Lines include their high specificity, reproducibility, and the potential to generate robust experimental data. Researchers and clinicians utilizing these cell lines can expect to achieve more accurate results, aiding in accelerated discoveries and innovations in the field of molecular biology.
Our company prides itself on its commitment to providing high-quality genetic tools that empower scientific advancement. With expertise in cellular genetics and a focus on delivering reliable products, we support researchers and clinicians in their quest for innovative solutions in understanding gene function and disease pathology.
Please note that all services are for research use only. Not intended for any clinical use.
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