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RNF125 Knockout Cell Lines

Gene: RNF125

Official Full Name: ring finger protein 125provided by HGNC

Gene Summary: This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00912 RNF125 Knockout cell line(HEK293) Human RNF125 1:3~1:6 Negative Online Inquiry
KO14475 RNF125 Knockout cell line (HCT 116) Human RNF125 1:2~1:4 Negative Online Inquiry

Background

RNF125 Gene Knockout Cell Lines are state-of-the-art biological tools designed for the precise study of the RNF125 gene's role in cellular processes. These cell lines feature a homozygous knockout of the RNF125 gene, achieved through advanced CRISPR-Cas9 gene-editing technology. This targeted approach allows researchers to investigate the specific contributions of RNF125 in various biological contexts, including its implications in cellular signaling, immune response, and cancer biology.

The key functionality of these cell lines lies in their ability to facilitate detailed studies of gene function and regulatory networks. By eliminating the RNF125 gene, researchers can observe changes in cellular behavior, protein interactions, and gene expression profiles, providing invaluable insights into the molecular mechanisms underpinning diseases and biological development. The ability to create isogenic background cell lines enhances experimental rigor and reproducibility, making these tools essential for advanced research.

The scientific importance of RNF125 Gene Knockout Cell Lines is underscored by their applications in fundamental research, drug discovery, and therapeutic development. They serve as invaluable resources for high-throughput screening of compounds that may restore normal function or inhibit aberrant activities associated with RNF125 dysregulation. Moreover, these knockout lines are poised for use in the development of personalized medicine strategies, where understanding gene function at the cellular level can inform targeted therapies.

Comparatively, RNF125 Gene Knockout Cell Lines offer several distinct advantages over conventional knockdown approaches. The complete knockout provides a definitive assessment of gene function, eliminating the ambiguity often associated with partial gene suppression methods like siRNA. Additionally, CRISPR-mediated gene editing ensures high specificity and efficiency, resulting in stable and reliable cell lines that can be easily cultured and maintained.

For researchers and clinicians, the value of RNF125 Gene Knockout Cell Lines extends beyond their experimental utility; they represent a cutting-edge approach to understanding gene function in health and disease. As a commitment to advancing biological research, our company brings expertise in genetic engineering and cell line development, ensuring that you receive high-quality, robust tools optimized for your research endeavors. This positions you to push the boundaries of scientific discovery, with the confidence that your experiments are grounded in precision and accuracy.

Please note that all services are for research use only. Not intended for any clinical use.

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