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RND2 Knockout Cell Lines

Gene: RND2

Official Full Name: Rho family GTPase 2provided by HGNC

Gene Summary: This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34303 RND2 Knockout cell line (HCT 116) Human RND2 1:2~1:4 Negative Online Inquiry
KO34304 RND2 Knockout cell line (HEK293) Human RND2 1:3~1:6 Negative Online Inquiry

Background

RND2 Gene Knockout Cell Lines are specifically engineered cellular models designed to lack the expression of the RND2 gene, a member of the Rho GTPase family known for its involvement in cellular signaling pathways that regulate various physiological processes. These cell lines offer researchers a powerful tool to investigate the downstream effects of RND2 depletion, allowing for the elucidation of its role in cell proliferation, differentiation, and movement.

The primary function of RND2 Gene Knockout Cell Lines lies in their ability to provide insights into the mechanisms through which RND2 affects cellular behavior. By observing the phenotypic changes that occur in these knockout cell lines, scientists can study the impact of RND2 on actin cytoskeleton dynamics, cell morphology, and migration patterns. This knowledge is crucial for understanding the molecular underpinnings of various diseases, including cancer, where aberrant Rho GTPase activity is commonly implicated.

The scientific importance of RND2 Gene Knockout Cell Lines extends to both basic research and clinical applications. In research settings, these models facilitate the dissection of RND2's contributions to cellular signaling networks and the exploration of potential therapeutic targets. Clinically, the findings derived from these studies could lead to novel approaches in treating conditions where RND2 plays a pivotal role, offering pathways for drug development and targeted therapies.

Compared to alternative models, RND2 Gene Knockout Cell Lines are particularly advantageous due to their high specificity and the ability to dissect gene function in a controlled environment. Unlike transient knockdown techniques, which often fail to maintain consistent gene expression changes, these stable knockout models provide robust and reproducible results, making them indispensable for long-term studies.

For researchers and clinicians alike, the value of RND2 Gene Knockout Cell Lines is evident; they enhance the understanding of cellular mechanisms and drive forward the development of effective treatment strategies. By utilizing these cell lines, investigators can gain a deeper understanding of the complexities of RND2 biology, ultimately leading to advancements in therapeutic interventions.

Our company specializes in the development of cutting-edge biological products, ensuring that researchers have access to high-quality, reliable tools that enhance scientific discovery. With a commitment to innovation and excellence, we provide researchers and clinicians with the resources necessary to push the boundaries of their work in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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