Gene: RMND1
Official Full Name: required for meiotic nuclear division 1 homologprovided by HGNC
Gene Summary: The protein encoded by this gene belongs to the evolutionary conserved sif2 family of proteins that share the DUF155 domain in common. This protein is thought to be localized in the mitochondria and involved in mitochondrial translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-11. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05311 | RMND1 Knockout cell line (HeLa) | Human | RMND1 | 1:3~1:6 | Negative | Online Inquiry |
KO05312 | RMND1 Knockout cell line (HCT 116) | Human | RMND1 | 1:2~1:4 | Negative | Online Inquiry |
KO05313 | RMND1 Knockout cell line (HEK293) | Human | RMND1 | 1:3~1:6 | Negative | Online Inquiry |
KO05314 | RMND1 Knockout cell line (A549) | Human | RMND1 | 1:3~1:4 | Negative | Online Inquiry |
RMND1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to eliminate the expression of the RMND1 gene, which plays a pivotal role in cellular processes such as ribosome biogenesis and translation. The targeted knockout of RMND1 is achieved using advanced CRISPR-Cas9 technology, enabling precise modification of the genome. This technique allows researchers to investigate the biological function of RMND1 by observing the resultant phenotypic changes in cellular behavior, signaling pathways, and overall cell vitality.
The primary function of RMND1 Gene Knockout Cell Lines is to serve as a critical tool for elucidating the gene's role in various cellular processes and disease models. By studying these knockout lines, researchers can explore the implications of RMND1 disruption on cell growth, differentiation, and apoptosis. This is particularly valuable in cancer research, where alterations in ribosomal protein synthesis and related pathways are frequently implicated. Furthermore, these cell lines are instrumental in drug discovery and validation efforts, allowing for the identification of therapeutic targets associated with ribosomal dysfunction.
What sets RMND1 Gene Knockout Cell Lines apart from other genetic modification tools is the robustness and reliability of CRISPR technology, which ensures high specificity and minimal off-target effects. Researchers can rely on these cell lines to deliver consistent results crucial for reproducible experimentation. Additionally, the thorough validation of these knockout models provides confidence in the data generated, making them essential for both preclinical and clinical research settings.
For researchers and clinicians seeking to deepen their understanding of RMND1-related mechanisms or to develop innovative therapeutic strategies, RMND1 Gene Knockout Cell Lines offer unparalleled value. They not only facilitate groundbreaking research but also enhance the potential for translating findings into clinical applications.
Our company, with its extensive expertise in genetic engineering and commitment to quality, ensures that each RMND1 Gene Knockout Cell Line is thoroughly validated and meets the highest standards of scientific rigor. We strive to empower the research community by providing cutting-edge tools that drive innovation and discovery in the field of molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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