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RMDN1 Knockout Cell Lines

Gene: RMDN1

Official Full Name: regulator of microtubule dynamics 1provided by HGNC

Gene Summary: Enables microtubule binding activity. Predicted to be involved in attachment of mitotic spindle microtubules to kinetochore and mitotic spindle organization. Located in mitotic spindle pole and spindle microtubule. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23014 RMDN1 Knockout cell line (HeLa) Human RMDN1 1:3~1:6 Negative Online Inquiry
KO23015 RMDN1 Knockout cell line (HCT 116) Human RMDN1 1:2~1:4 Negative Online Inquiry
KO23016 RMDN1 Knockout cell line (HEK293) Human RMDN1 1:3~1:6 Negative Online Inquiry
KO23017 RMDN1 Knockout cell line (A549) Human RMDN1 1:3~1:4 Negative Online Inquiry

Background

RMDN1 Gene Knockout Cell Lines are cellular models specifically engineered to disrupt the RMDN1 gene, a critical component involved in various cellular processes, including ribosome assembly and stress response pathways. This product serves as an invaluable tool for researchers studying the functional implications of RMDN1 deficiency in human cells, allowing for the exploration of its role in diseases such as cancer, neurodegeneration, and cellular aging.

The primary function of the RMDN1 Gene Knockout Cell Lines lies in their ability to facilitate targeted gene analysis through the absence of RMDN1 expression. This is achieved via CRISPR/Cas9 technology, which enables precise modifications to the genome, thereby creating a reliable platform for observing phenotypic and biochemical changes. Researchers can investigate downstream effects of RMDN1 loss, such as alterations in cell proliferation, apoptosis, and stress response mechanisms, offering insights into potential therapeutic targets.

In terms of scientific importance, these knockout cell lines represent a significant advancement in the field of molecular biology and genetics. They are particularly valuable for examining gene function and its implications in various pathologies, as well as in drug discovery and development sectors. Clinical settings benefit from these tools in translational research, as they provide a biological basis for understanding the underlying mechanisms of diseases related to RMDN1 dysfunction.

Compared to alternative cell lines, RMDN1 Gene Knockout Cell Lines are meticulously validated and characterized, ensuring consistency and reliability in experimental results. Their specificity in targeting the RMDN1 gene allows researchers to bypass off-target effects commonly encountered with less sophisticated gene-editing strategies. Furthermore, these lines are compatible with a wide range of biochemical assays, making them versatile for multifaceted research applications.

The value of RMDN1 Gene Knockout Cell Lines extends to researchers and clinicians who are seeking to elucidate the complex roles of this gene in health and disease. By utilizing this cutting-edge product, users can enhance their understanding of cellular mechanisms and potentially develop innovative therapeutic approaches.

Our company, dedicated to advancing scientific knowledge and biotechnological applications, takes pride in offering high-quality, rigorously tested biological products. Our expertise in genetics and cell biology ensures that researchers and clinicians are equipped with the tools necessary to drive impactful discoveries in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

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