Gene: RIOK3
Official Full Name: RIO kinase 3provided by HGNC
Gene Summary: This gene was first identified by the similarity of its product to the Aspergillus nidulans SUDD protein. This gene is now recognized as a member of the right open reading frame (RIO) kinase gene family. This gene encodes a serine/threonine kinase that localizes to the cytoplasm and plays a role in the processing of the pre-40 S ribosomal subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02155 | RIOK3 Knockout cell line (HeLa) | Human | RIOK3 | 1:3~1:6 | Negative | Online Inquiry |
KO02156 | RIOK3 Knockout cell line (HCT 116) | Human | RIOK3 | 1:2~1:4 | Negative | Online Inquiry |
KO02157 | RIOK3 Knockout cell line (HEK293) | Human | RIOK3 | 1:3~1:6 | Negative | Online Inquiry |
KO02158 | RIOK3 Knockout cell line (A549) | Human | RIOK3 | 1:3~1:4 | Negative | Online Inquiry |
RIOK3 Gene Knockout Cell Lines are genetically modified cell lines in which the RIOK3 gene has been disrupted using cutting-edge CRISPR-Cas9 gene-editing technology. RIOK3, a pivotal gene involved in ribosome biogenesis and cellular growth regulation, is essential for various cellular processes. By creating knockout models, researchers can effectively investigate the specific functions of RIOK3, enabling deeper insights into the cellular pathways it governs.
The primary function of these knockout cell lines lies in their ability to elucidate the biological roles of RIOK3 in cellular proliferation, differentiation, and response to stress. By silencing RIOK3, researchers can observe changes in pathways that may contribute to oncogenesis or metabolic disorders, facilitating important discoveries in cancer biology, neurodegenerative diseases, and developmental research. The precise mechanism of action involves the removal of critical sequences within the RIOK3 gene, allowing for the study of altered phenotypic traits without the confounding influence of its expression.
Scientifically, RIOK3 Gene Knockout Cell Lines hold immense value in both research and clinical applications. They serve as vital tools for drug discovery, toxicology studies, and functional genomics, supporting the development of targeted therapies that address specific molecular mechanisms linked to disease. Compared to traditional cell lines, these engineered models provide a more representative platform for studying complex biological questions, effectively bridging the gap between basic research and clinical application.
One of the unique selling points of our RIOK3 Gene Knockout Cell Lines is their robust validation and characterization, ensuring high-quality performance that meets the stringent requirements of modern research. Additionally, these cell lines come with extensive documentation and support, empowering researchers to seamlessly integrate them into their investigations.
Choosing RIOK3 Gene Knockout Cell Lines not only enhances your experimental rigor but also accelerates the pace of discovery in various fields of biomedical research. Our commitment to innovation and quality positions our company as a leader in providing fundamental tools essential for advancing scientific knowledge and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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