Gene: RIN1
Official Full Name: Ras and Rab interactor 1provided by HGNC
Gene Summary: Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within associative learning; memory; and negative regulation of synaptic plasticity. Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08850 | RIN1 Knockout cell line (HeLa) | Human | RIN1 | 1:3~1:6 | Negative | Online Inquiry |
KO08851 | RIN1 Knockout cell line (HCT 116) | Human | RIN1 | 1:2~1:4 | Negative | Online Inquiry |
KO08852 | RIN1 Knockout cell line (A549) | Human | RIN1 | 1:3~1:4 | Negative | Online Inquiry |
RIN1 Gene Knockout Cell Lines are meticulously engineered human cell lines that have undergone targeted genetic modification to disrupt the expression of the RIN1 gene, which plays a critical role in cellular signal transduction and regulation of various cellular processes. By employing advanced CRISPR/Cas9 gene editing technology, these cell lines provide a powerful tool for researchers investigating the biological pathways influenced by RIN1, including its involvement in cellular growth, differentiation, and apoptosis.
The primary function of RIN1 is as a regulator within the Ras signaling pathway, which is essential in mediating cell proliferation and survival. The knockout of RIN1 allows for the elucidation of its role in oncogenic processes, as well as its potential interactions with other key regulatory proteins. By utilizing RIN1 Gene Knockout Cell Lines, scientists can better understand the downstream effects of RIN1 loss, thus contributing to the development of novel therapeutic strategies for cancer and other diseases characterized by aberrant signaling pathways.
The scientific importance of these cell lines extends to both research and clinical applications. They provide a valuable model to study the implications of RIN1 in tumorigenesis and therapeutic resistance, offering insights into the molecular mechanisms underlying various malignancies. Researchers can leverage these cell lines to validate potential drug targets or evaluate the efficacy of novel compounds in a controlled environment.
When compared to traditional knockout methods, RIN1 Gene Knockout Cell Lines present significant advantages, including reproducibility, efficiency in gene editing, and a ready-to-use platform for immediate experimentation. This strategic lever provides researchers with a consistent background for comparative studies, ultimately expediting timelines for discovery and innovation.
In conclusion, RIN1 Gene Knockout Cell Lines represent an indispensable resource for researchers and clinicians dedicated to unraveling the complexities of cancer biology and developing targeted therapies. Backed by our established expertise in biological products and advanced genetic engineering techniques, we are committed to delivering high-quality solutions that empower researchers in their quest for knowledge and therapeutic advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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