Home / RIC1 Knockout Cell Lines

RIC1 Knockout Cell Lines

Gene: RIC1

Official Full Name: RIC1 homolog, RAB6A GEF complex partner 1provided by HGNC

Gene Summary: Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including positive regulation of GTPase activity; regulation of extracellular matrix constituent secretion; and retrograde transport, endosome to Golgi. Located in cytosol and membrane. Part of Ric1-Rgp1 guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14550 RIC1 Knockout cell line (HeLa) Human RIC1 1:3~1:6 Negative Online Inquiry
KO14551 RIC1 Knockout cell line (HCT 116) Human RIC1 1:2~1:4 Negative Online Inquiry
KO14552 RIC1 Knockout cell line (HEK293) Human RIC1 1:3~1:6 Negative Online Inquiry
KO14553 RIC1 Knockout cell line (A549) Human RIC1 1:3~1:4 Negative Online Inquiry

Background

RIC1 Gene Knockout Cell Lines are specially engineered cellular models that possess a targeted deletion of the RIC1 gene, which is pivotal in regulating intracellular trafficking and membrane dynamics. These knockout cell lines serve as essential tools for researchers studying the molecular pathways underlying vesicular transport and endosomal sorting mechanisms. By utilizing these cell lines, scientists can effectively elucidate the functional roles of the RIC1 protein and its contributions to cellular processes such as cell signaling, homeostasis, and disease progression.

The primary function of RIC1 involves acting as a guanine nucleotide exchange factor (GEF) that activates ADP ribosylation factor (ARF) proteins, thereby influencing the cytosolic recycling and trafficking of proteins and lipids. The RIC1 Gene Knockout Cell Lines offer unique insights into the consequences of RIC1 loss on cellular morphology and function, facilitating breakthroughs in understanding various pathologies, including cancer, neurodegenerative disorders, and infectious diseases.

The scientific importance of these knockout cell lines is underscored by their potential applications in both research and clinical settings. Researchers can leverage these cells to conduct high-throughput screenings for potential drug candidates, investigate gene functions in various biological contexts, or explore new therapeutic strategies targeting vesicle trafficking defects.

Compared to alternative models, the RIC1 Gene Knockout Cell Lines provide a specific and robust tool for studying RIC1-related pathways, ensuring high-fidelity results that reflect the physiological relevance of findings. This specificity minimizes off-target effects commonly observed with broad-spectrum gene editing techniques and enables a deeper understanding of RIC1 biology.

For researchers, clinicians, and innovators in the field of molecular biology, the accessibility and functionality of RIC1 Gene Knockout Cell Lines represent an invaluable asset for advancing knowledge and developing future therapies. Our company has established a strong reputation for providing high-quality biological products, leveraging cutting-edge technology and extensive expertise in gene editing to support the scientific community in reaching its research goals with precision and reliability.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.