Gene: RIBC1
Official Full Name: RIB43A domain with coiled-coils 1provided by HGNC
Gene Summary: Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14554 | RIBC1 Knockout cell line (HeLa) | Human | RIBC1 | 1:3~1:6 | Negative | Online Inquiry |
KO14555 | RIBC1 Knockout cell line (HEK293) | Human | RIBC1 | 1:3~1:6 | Negative | Online Inquiry |
KO14556 | RIBC1 Knockout cell line (A549) | Human | RIBC1 | 1:3~1:4 | Negative | Online Inquiry |
RIBC1 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to facilitate the study of the RIBC1 gene's functionality by creating a complete loss of its expression. This innovative product enables researchers to investigate the biological roles, signaling pathways, and cellular processes influenced by RIBC1, which is implicated in various cellular functions such as ribosome biogenesis and protein synthesis regulation. By employing CRISPR-Cas9 gene-editing technology, RIBC1 gene knockout ensures precise excision of the target gene, allowing scientists to observe the phenotypic consequences of its absence.
The primary function of these knockout cell lines is to serve as a model system for elucidating the gene’s biological significance in both healthy and disease states. Specifically, researchers can assess how RIBC1 disruption alters cellular responses to stress, growth regulation, and the etiology of diseases such as cancer or neurodegenerative disorders. Additionally, these cell lines can be invaluable in drug discovery and development, allowing for the identification of potential therapeutic targets by evaluating the effects of various compounds in a controlled environment.
Compared to traditional gene-silencing techniques such as siRNA or shRNA, RIBC1 gene knockout cell lines provide a more permanent and comprehensive assessment of gene function, eliminating potential off-target effects or transient gene expression alterations. Moreover, these cell lines are optimized for high throughput applications, significantly enhancing throughput in drug screening processes.
For researchers and clinicians, the RIBC1 Gene Knockout Cell Lines represent a critical resource in understanding basic cellular biology and advancing translational research. The ability to manipulate gene expression with precise control means these cell lines can help validate biomarkers, identify novel therapeutic pathways, and foster advances in personalized medicine.
Our company prides itself on being at the forefront of genetic research products, leveraging cutting-edge techniques and expertise to provide high-quality biological products that facilitate scientific discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.