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RHOU Knockout Cell Lines

Gene: RHOU

Official Full Name: ras homolog family member Uprovided by HGNC

Gene Summary: This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20657 RHOU Knockout cell line (HCT 116) Human RHOU 1:2~1:4 Negative Online Inquiry
KO20658 RHOU Knockout cell line (HEK293) Human RHOU 1:3~1:6 Negative Online Inquiry
KO20659 RHOU Knockout cell line (A549) Human RHOU 1:3~1:4 Negative Online Inquiry

Background

RHOU Gene Knockout Cell Lines represent a cutting-edge biological product that allows researchers to study the function of the RHOU gene through the complete absence of its expression. RHOU, a member of the Rho GTPase family, plays a critical role in cellular signaling pathways, influencing various biological processes such as cell migration, proliferation, and differentiation. These knockout cell lines are meticulously engineered to provide a versatile platform for investigating the gene's role in both normal physiology and pathological conditions, including cancer metastasis and tissue remodeling.

The primary function of RHOU Gene Knockout Cell Lines is to facilitate a comprehensive understanding of RHOU's contributions to cellular behavior. By utilizing CRISPR/Cas9 technology for precise gene editing, these cell lines ensure a complete knockout of RHOU, providing clarity in experimental outcomes. Researchers can leverage these models to systematically explore gene function through various assays, including migration and invasion studies, and gain insights into the downstream effects on cellular signaling pathways.

The scientific importance of RHOU Gene Knockout Cell Lines is underscored by their applications in both research and clinical settings. They serve as invaluable tools for cancer biology studies, immune response investigations, and drug development, enabling scientists to discover novel therapeutic targets and understand disease mechanisms on a granular level. Their utilization can lead to significant advancements in personalized medicine and targeted therapies.

Compared to alternative models, RHOU Gene Knockout Cell Lines provide a distinct advantage in terms of specific gene targeting and the fidelity of results. Unlike traditional methods, which may rely on transient transfections or RNA interference, the knockout approach eliminates off-target effects and delivers more consistent and reproducible data.

For researchers and clinicians striving to push the boundaries of biological discovery, the availability of RHOU Gene Knockout Cell Lines represents an invaluable resource that accelerates research timelines and enhances the quality of findings. Moreover, our company prides itself on its expertise in developing high-quality genetic models and cutting-edge biotechnologies, ensuring that our clients have access to top-tier products that empower scientific innovation and clinical breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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