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RHOF Knockout Cell Lines

Gene: RHOF

Official Full Name: ras homolog family member F, filopodia associatedprovided by HGNC

Gene Summary: Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in actin filament organization. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21652 RHOF Knockout cell line (HeLa) Human RHOF 1:3~1:6 Negative Online Inquiry
KO21653 RHOF Knockout cell line (HCT 116) Human RHOF 1:2~1:4 Negative Online Inquiry
KO21654 RHOF Knockout cell line (HEK293) Human RHOF 1:3~1:6 Negative Online Inquiry
KO21655 RHOF Knockout cell line (A549) Human RHOF 1:3~1:4 Negative Online Inquiry

Background

RHOF Gene Knockout Cell Lines are specialized cell culture models designed to investigate the biological roles of the RHOF gene, which encodes a member of the Rho family of GTPases. These knockout lines are engineered to lack functional RHOF expression, allowing researchers to study the gene's effects in metabolic pathways, signal transduction, and cellular morphology without confounding variables from the gene's activity.

The primary function of RHOF Gene Knockout Cell Lines is to elucidate the cellular mechanisms influenced by the absence of RHOF. By disrupting this gene, these cell lines enable detailed analyses of changes in actin cytoskeleton dynamics, cell adhesion, migration, and proliferation. This is particularly critical for understanding RHOF's roles in various physiological and pathological processes, including cancer development and progression.

Scientifically, the availability of RHOF Gene Knockout Cell Lines has significant implications for both basic research and translational applications. These models facilitate investigations into novel therapeutic targets associated with RHOF, contributing to advancements in drug development and precision medicine strategies. Moreover, they provide a platform for exploring gene-gene interactions and signaling cascades that may involve RHOF, offering valuable insights into complex cellular networks.

Compared to alternative models, such as wild-type cells or general knockout systems, RHOF Gene Knockout Cell Lines offer the specificity required for focused studies on RHOF-mediated pathways. This specificity minimizes the risk of off-target effects, enhances reproducibility, and provides more robust data for experimental setups.

For researchers and clinicians, the value of RHOF Gene Knockout Cell Lines lies in their ability to generate high-quality, reliable data integral to the understanding of critical biological questions. The rigorous characterization and validation of these cell lines ensure that they are appropriate for various experimental protocols, making them an essential tool in both academic and industrial research settings.

Backed by our company's extensive expertise in gene-editing technologies and cell line development, we are committed to providing researchers with high-quality biological products that facilitate groundbreaking discoveries in molecular biology and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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