Home / RHOBTB2 Knockout Cell Lines

RHOBTB2 Knockout Cell Lines

Gene: RHOBTB2

Official Full Name: Rho related BTB domain containing 2provided by HGNC

Gene Summary: The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29655 RHOBTB2 Knockout cell line (HeLa) Human RHOBTB2 1:3~1:6 Negative Online Inquiry
KO29656 RHOBTB2 Knockout cell line (HCT 116) Human RHOBTB2 1:2~1:4 Negative Online Inquiry
KO29657 RHOBTB2 Knockout cell line (HEK293) Human RHOBTB2 1:3~1:6 Negative Online Inquiry
KO29658 RHOBTB2 Knockout cell line (A549) Human RHOBTB2 1:3~1:4 Negative Online Inquiry

Background

RHOBTB2 Gene Knockout Cell Lines are a vital biological tool designed for advanced research in cellular and molecular biology. These cell lines are engineered to lack the RHOBTB2 gene, a member of the Rho family of GTPases, which is implicated in various cellular processes such as cytoskeletal dynamics, signal transduction, and cell proliferation. By providing a system that specifically lacks this gene, researchers have the opportunity to investigate the functional roles of RHOBTB2 in disease mechanisms, particularly its association with cancer progression and metastasis.

The primary mechanism by which these knockout cell lines operate is through the complete disruption of RHOBTB2 expression, which results in altered cellular responses. This alteration allows scientists to study the downstream effects of RHOBTB2 absence, including changes in cell morphology, adhesion properties, and migration capabilities. The implications of these studies are significant, providing valuable insights into potential targets for therapeutic intervention in diseases that feature aberrant Rho signaling.

In terms of scientific importance, RHOBTB2 Gene Knockout Cell Lines are indispensable for elucidating molecular pathways in cancer biology and other related fields. Their application extends to drug discovery, where understanding the role of RHOBTB2 can lead to the identification of novel therapeutic targets. The use of these cell lines can aid in validating drug efficacy and safety in preclinical studies.

What sets our RHOBTB2 Gene Knockout Cell Lines apart from alternatives is their high specificity and reliability, resulting from rigorous quality control measures during the cell line development process. Each line is extensively characterized for purity and consistency, ensuring that researchers can obtain reproducible results.

For researchers and clinicians, these knockout cell lines represent a valuable resource for innovative studies that can advance their understanding of complex biological systems. By integrating cutting-edge genetic engineering techniques with robust cellular models, our product empowers scientific inquiry and enhances experimental outcomes.

With extensive expertise in cellular model systems and a commitment to advancing bioresearch, our company delivers high-quality biological products that facilitate meaningful discoveries in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.