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RHBDL3 Knockout Cell Lines

Gene: RHBDL3

Official Full Name: rhomboid like 3provided by HGNC

Gene Summary: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30412 RHBDL3 Knockout cell line (HeLa) Human RHBDL3 1:3~1:6 Negative Online Inquiry
KO30413 RHBDL3 Knockout cell line (HCT 116) Human RHBDL3 1:2~1:4 Negative Online Inquiry
KO30414 RHBDL3 Knockout cell line (HEK293) Human RHBDL3 1:3~1:6 Negative Online Inquiry
KO30415 RHBDL3 Knockout cell line (A549) Human RHBDL3 1:3~1:4 Negative Online Inquiry

Background

RHBDL3 Gene Knockout Cell Lines are specialized biological models created to study the function and role of the RHBDL3 gene in various cellular processes. These cell lines are engineered using advanced CRISPR/Cas9 gene-editing technology, resulting in the precise deletion of the RHBDL3 gene. This targeted approach allows researchers to investigate the gene's involvement in mechanisms such as cellular signaling, metabolism, and its implications in diseases.

The RHBDL3 gene is known to encode a protein that operates as a rhomboid protease, which plays a critical role in proteolytic processes within the endoplasmic reticulum. By utilizing the RHBDL3 knockout cell lines, researchers can elucidate the consequences of RHBDL3 gene loss on protein processing and examine its broader implications in pathological conditions, including cancer and neurodegenerative disorders. Moreover, these knockout cells can serve as a valuable tool for drug screening and the development of novel therapeutic strategies.

One of the significant advantages of the RHBDL3 knockout cell lines is their specificity and high efficiency in gene inactivation compared to traditional knockdown methods, such as siRNA, which may lead to incomplete inhibition. This fidelity enables scientists to draw more accurate conclusions regarding gene function and interactions. Furthermore, the consistency and reproducibility of these cell lines facilitate standardization in experiments, enhancing the reliability of data across studies.

Overall, RHBDL3 Gene Knockout Cell Lines present a powerful resource for researchers seeking to decode complex biological pathways and contribute to the advancement of clinical knowledge. By providing an essential tool for innovative research, our company, a leader in the development of genetic tools and cell models, is committed to delivering high-quality products that empower scientists in their quest for discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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