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RHBDF1 Knockout Cell Lines

Gene: RHBDF1

Official Full Name: rhomboid 5 homolog 1provided by HGNC

Gene Summary: Predicted to enable growth factor binding activity and serine-type endopeptidase activity. Involved in several processes, including negative regulation of protein secretion; regulation of epidermal growth factor receptor signaling pathway; and regulation of proteasomal protein catabolic process. Located in Golgi membrane and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20449 RHBDF1 Knockout cell line (HeLa) Human RHBDF1 1:3~1:6 Negative Online Inquiry
KO20450 RHBDF1 Knockout cell line (HCT 116) Human RHBDF1 1:2~1:4 Negative Online Inquiry
KO20451 RHBDF1 Knockout cell line (HEK293) Human RHBDF1 1:3~1:6 Negative Online Inquiry
KO20452 RHBDF1 Knockout cell line (A549) Human RHBDF1 1:3~1:4 Negative Online Inquiry

Background

RHBDF1 Gene Knockout Cell Lines represent a sophisticated tool in molecular biology, specifically designed to facilitate the study of the RHBDF1 gene and its implications in various biological processes. These cell lines are genetically engineered to exhibit a complete knockout of the RHBDF1 gene, allowing researchers to observe the resultant phenotypic changes. This knockout enables in-depth investigations into the role of RHBDF1 in cell signaling, protein turnover, and immune response, particularly its involvement in the regulation of epidermal growth factor receptor (EGFR) pathway signaling.

The functionality of RHBDF1 Gene Knockout Cell Lines lies in their ability to mimic pathological states associated with dysregulations in the RHBDF1 gene. By observing the differences in cellular behavior, proliferation, and signaling pathways in these knockout models compared to wild-type cell lines, researchers can elucidate the mechanisms underlying various diseases, including certain cancers and skin disorders. This product is particularly invaluable in both academic and clinical settings, where it serves as a foundational platform for drug discovery, gene therapy research, and understanding disease mechanisms.

What sets RHBDF1 Gene Knockout Cell Lines apart from alternative products is their robust validation and the detailed characterization that supports experimental reproducibility. These cell lines have been subjected to rigorous testing to ensure the reliability of results, making them a superior choice for researchers striving for accuracy in their work. Additionally, the availability of a standardized knockout model streamlines experimentation, enabling rapid analysis and integration into various research studies.

For researchers and clinicians, the value of RHBDF1 Gene Knockout Cell Lines is multifaceted. The ability to selectively manipulate gene expression opens up countless avenues for exploration in drug development and therapeutic strategies, particularly in diseases where RHBDF1 may play a crucial role. Our company brings immense expertise in gene editing technologies, ensuring that our products not only meet a high standard of quality but also provide outstanding service and support to the scientific community. With a commitment to advancing research, we empower your discoveries with precision-engineered biological tools tailored to meet your experimental needs.

Please note that all services are for research use only. Not intended for any clinical use.

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