Gene: RGMB
Official Full Name: repulsive guidance molecule BMP co-receptor bprovided by HGNC
Gene Summary: RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14570 | RGMB Knockout cell line (HeLa) | Human | RGMB | 1:3~1:6 | Negative | Online Inquiry |
KO14571 | RGMB Knockout cell line (HCT 116) | Human | RGMB | 1:2~1:4 | Negative | Online Inquiry |
KO14572 | RGMB Knockout cell line (HEK293) | Human | RGMB | 1:3~1:6 | Negative | Online Inquiry |
KO14573 | RGMB Knockout cell line (A549) | Human | RGMB | 1:3~1:4 | Negative | Online Inquiry |
RGMB Gene Knockout Cell Lines are highly specialized biological tools designed for the precise study of the RGMB gene's function in cellular processes. Utilizing CRISPR-Cas9 genome-editing technology, these cell lines enable researchers to create a complete knockout of RGMB, facilitating the investigation of its role in various biological pathways, including regulation of embryonic development, neural differentiation, and tumorigenesis.
The key function of RGMB Gene Knockout Cell Lines lies in their ability to provide a controlled environment wherein the RGMB gene is absent. This mechanism allows for the observation of phenotypic changes and the elucidation of molecular mechanisms that are otherwise masked in wild-type versions of the cell lines. Researchers can employ these knockout lines to dissect the signaling pathways influenced by RGMB and to identify potential therapeutic targets for diseases linked to its dysregulation.
The scientific importance of RGMB Gene Knockout Cell Lines is underscored by their application in both fundamental research and clinical settings. They serve as invaluable tools for cancer research, neurobiology, and regenerative medicine, enabling scientists to pioneer novel approaches to treatment and deepen our understanding of various pathologies. The ability to study gene function in a targeted manner accelerates the advancement of gene therapies and personalized medicine strategies.
Comparatively, unlike conventional knockout models that may exhibit unintended genetic modifications or compensatory mechanisms, RGMB Gene Knockout Cell Lines provide a higher degree of specificity and reliability. Their streamlined generation process, combined with validated performance, offers researchers a unique advantage in attaining reproducible and robust experimental outcomes.
Given the increasing demand within the scientific community for precise cellular models, RGMB Gene Knockout Cell Lines represent a critical resource for researchers and clinicians aiming to address pressing biomedical questions. By investing in these gene knockout cell lines, scientists will be equipped with superior tools to drive innovation and discovery in their respective fields. Our company, a leader in biotechnological advancements, is committed to delivering high-quality biological products like RGMB Gene Knockout Cell Lines that empower the research community and foster breakthroughs in health and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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