Gene: RGL4
Official Full Name: ral guanine nucleotide dissociation stimulator like 4provided by HGNC
Gene Summary: This oncogene encodes a protein similar to guanine nucleotide exchange factor Ral guanine dissociation stimulator. Increased expression of this gene leads to translocation of the encoded protein to the cell membrane. The encoded protein can activate several pathways, including the Ras-Raf-MEK-ERK cascade. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14576 | RGL4 Knockout cell line (HEK293) | Human | RGL4 | 1:3~1:6 | Negative | Online Inquiry |
RGL4 Gene Knockout Cell Lines are genetically modified cells designed to specifically lack the RGL4 gene, which encodes for proteins involved in various biological processes, including cell signaling and growth. These cell lines serve as pivotal tools for dissecting the functional roles of RGL4 in cellular networks, enabling researchers to explore its contributions in health and disease contexts. By utilizing CRISPR-Cas9 technology for the knockout process, these cell lines exhibit precise genetic alterations, allowing for in-depth analysis of RGL4-related pathways and phenotypes.
The key function of RGL4 Gene Knockout Cell Lines lies in their ability to facilitate studies on cell proliferation, differentiation, and survival mechanisms, particularly in relation to cancer research. By providing a controlled environment to investigate the absence of RGL4, researchers can gain valuable insights into its role in tumorigenesis, offering an effective model for the evaluation of therapeutic targets. In clinical settings, the understanding garnered from these studies could guide the development of novel treatment strategies that capitalize on the modulation of RGL4 pathways.
Compared to traditional cell lines, RGL4 Gene Knockout Cell Lines present unique advantages including bespoke genetic alterations that ensure high specificity to RGL4, reduced off-target effects, and the potential for reproducibility in experimental setups. Additionally, the ease of use with standard cell culture techniques makes them accessible for laboratories of varying expertise.
The value of RGL4 Gene Knockout Cell Lines extends beyond research; they are integral for developing therapeutic interventions, optimizing drug delivery systems, and even personalizing medicine approaches based on individual genetic backgrounds. Their comprehensive application range positions them as indispensable resources for both researchers and clinicians aiming to advance understanding within the realms of cell biology and medicine.
Our company specializes in providing high-quality biological tools, with a commitment to advancing molecular research through innovative products such as RGL4 Gene Knockout Cell Lines, ensuring that our partners are equipped with the best resources to make meaningful scientific discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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