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REXO5 Knockout Cell Lines

Gene: REXO5

Official Full Name: RNA exonuclease 5provided by HGNC

Gene Summary: Predicted to enable exonuclease activity. Predicted to be involved in rRNA 3'-end processing. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25666 REXO5 Knockout cell line (HeLa) Human REXO5 1:3~1:6 Negative Online Inquiry
KO25667 REXO5 Knockout cell line (HCT 116) Human REXO5 1:2~1:4 Negative Online Inquiry
KO25668 REXO5 Knockout cell line (HEK293) Human REXO5 1:3~1:6 Negative Online Inquiry
KO25669 REXO5 Knockout cell line (A549) Human REXO5 1:3~1:4 Negative Online Inquiry

Background

REXO5 Gene Knockout Cell Lines are a series of genetically modified cell lines specifically designed to facilitate the study of RNA processing and its implications in cellular functionality and disease mechanisms. The REXO5 gene encodes a putative RNA exonuclease that plays a crucial role in the degradation of RNA molecules, thereby influencing gene expression and the overall RNA lifecycle within the cell. By providing a knockout version of the REXO5 gene, these cell lines enable researchers to investigate the phenotypic alterations resulting from the loss of this essential regulatory function.

The key mechanism of action involves the selective elimination of REXO5 expression, enabling scientists to explore downstream effects on RNA stability, turnover rates, and the modulation of related signaling pathways. This functional silencing permits researchers to unravel the complex dynamics of RNA metabolism, contributing to a more comprehensive understanding of cellular responses in normal physiology as well as various pathological conditions.

In the scientific community, REXO5 Gene Knockout Cell Lines have significant implications in both research and clinical contexts, particularly in the areas of cancer biology, neurobiology, and developmental biology. These models are indispensable tools for elucidating the role of RNA degradation in diseases where aberrant RNA processing is implicated, thus facilitating the development of novel therapeutic strategies.

One of the distinguishing advantages of REXO5 knockout cell lines over competing products is their specificity and reliability. Unlike general RNA interference (RNAi) techniques that may elicit off-target effects, these knockout lines provide a clean, genetic approach that fosters reproducible outcomes. As a result, researchers can attain more robust data with higher confidence in their results, expediting breakthroughs in their studies.

For researchers and clinicians aiming to deepen their understanding of RNA biology and related disease pathways, REXO5 Gene Knockout Cell Lines represent a valuable addition to their experimental arsenal. By utilizing these advanced cell lines, users can amplify their research capabilities, driving innovation and progress in their respective fields.

Our company boasts extensive expertise in the production of high-quality genetic models, ensuring that our REXO5 Gene Knockout Cell Lines are rigorously validated and optimized for exceptional performance in the laboratory. With a commitment to scientific excellence, we provide researchers with cutting-edge tools that empower them to achieve their investigative goals.

Please note that all services are for research use only. Not intended for any clinical use.

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