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REXO4 Knockout Cell Lines

Gene: REXO4

Official Full Name: REX4 homolog, 3'-5' exonucleaseprovided by HGNC

Gene Summary: Enables DNA binding activity and nuclease activity. Involved in DNA catabolic process and DNA repair. Located in nuclear speck and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20775 REXO4 Knockout cell line (HeLa) Human REXO4 1:3~1:6 Negative Online Inquiry
KO20776 REXO4 Knockout cell line (HCT 116) Human REXO4 1:2~1:4 Negative Online Inquiry
KO20777 REXO4 Knockout cell line (HEK293) Human REXO4 1:3~1:6 Negative Online Inquiry
KO20778 REXO4 Knockout cell line (A549) Human REXO4 1:3~1:4 Negative Online Inquiry

Background

REXO4 Gene Knockout Cell Lines are precision-engineered cellular models designed to study the functional implications of the REXO4 gene in various biological contexts. These knockout cell lines have been meticulously developed through CRISPR-Cas9 technology, allowing for targeted disruption of the REXO4 gene, a crucial component involved in RNA processing and cellular stress responses. By eliminating this gene, researchers can now study the resultant phenotypic changes and understand the gene's role in cellular mechanisms such as proliferation, apoptosis, and response to environmental stressors.

The primary function of REXO4 is linked to RNA metabolism, influencing mRNA stability and translation, thus affecting protein synthesis within the cell. Disrupting REXO4 provides insights into its contributions to cell survival and function, making it an invaluable tool for scientists investigating pathways implicated in cancer, neurodegenerative diseases, and other conditions influenced by RNA dynamics. These knockout cell lines facilitate high-throughput screening and allow researchers to elucidate the gene's role in various biological processes more effectively.

REXO4 Gene Knockout Cell Lines distinguish themselves from traditional cell models by offering a precise, reproducible approach to gene function analysis with minimal off-target effects. Unlike conventional methods, our models ensure robust gene editing, making them an ideal choice for researchers who require reliability in their experimental designs.

By utilizing REXO4 Gene Knockout Cell Lines, researchers and clinicians can advance their investigations into gene function and disease mechanisms with confidence in the accuracy and consistency of their results. These cell lines represent a significant leap forward in gene analysis technology, allowing for a deeper understanding of complex biological systems and paving the way for potential therapeutic interventions.

Your decision to use REXO4 Gene Knockout Cell Lines reflects a commitment to high-quality research, underpinned by our company's extensive expertise in molecular biology and genetic engineering. We are dedicated to providing innovative solutions that empower the scientific community to achieve novel discoveries and breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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