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RERG Knockout Cell Lines

Gene: RERG

Official Full Name: RAS like estrogen regulated growth inhibitorprovided by HGNC

Gene Summary: RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24357 RERG Knockout cell line (HeLa) Human RERG 1:3~1:6 Negative Online Inquiry
KO24358 RERG Knockout cell line (HEK293) Human RERG 1:3~1:6 Negative Online Inquiry

Background

RERG Gene Knockout Cell Lines are genetically engineered model systems designed to study the function of the RERG gene, which encodes a member of the Ras family of small GTPases. By selectively knocking out the RERG gene, these cell lines allow researchers to elucidate its role in various cellular processes such as proliferation, differentiation, and apoptosis. This product provides a valuable resource for understanding RERG's contribution to oncogenic pathways and its potential implications in cancer biology.

The key functions of RERG Gene Knockout Cell Lines center around their ability to facilitate comparative studies that implicate the RERG gene in various signaling pathways. These cell lines can exhibit altered responses to growth factors, changes in cell morphology, and modified expression profiles of downstream effectors. By utilizing these knockout models, researchers can effectively assess the functional consequences of RERG loss in a controlled environment, thus enhancing the understanding of its biological mechanisms.

The scientific importance of these cell lines extends into both research and clinical settings, offering insights for the development of targeted therapies in oncology. Given that mutations and dysregulation of RERG have been linked to various cancers, these knockout models can serve as crucial platforms for drug discovery and validation, making them instrumental for translational research.

Compared to alternative gene knockouts, RERG Gene Knockout Cell Lines stand out due to their specific targeting of a less-studied gene with significant implications in malignancies. They provide researchers with a unique opportunity to dissect the role of RERG in specific cancer types in a rapid and efficient manner. Moreover, the availability of these cell lines simplifies experimental design, reducing both time and resource expenditure.

For researchers and clinicians focused on uncovering the complexities of cancer biology and pursuing novel therapeutic approaches, RERG Gene Knockout Cell Lines represent an invaluable tool. By integrating these models into research programs, users can propel their investigation into the mechanisms of cancer and further their contributions to precision medicine.

Our company brings extensive expertise in the development of high-quality cellular models that empower scientific discoveries. We are committed to providing exceptional products that meet the evolving needs of the research community, ensuring that our customers have the best tools available to advance their investigations.

Please note that all services are for research use only. Not intended for any clinical use.

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