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RBPMS2 Knockout Cell Lines

Gene: RBPMS2

Official Full Name: RNA binding protein, mRNA processing factor 2provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the RNA recognition motif (RRM)-containing protein family and is involved in the development and dedifferentiation of digestive smooth muscle cells. The encoded protein functions as a homodimer and indirectly inhibits the bone morphogenetic protein pathway. [provided by RefSeq, Aug 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14650 RBPMS2 Knockout cell line (HeLa) Human RBPMS2 1:3~1:6 Negative Online Inquiry
KO14651 RBPMS2 Knockout cell line (HCT 116) Human RBPMS2 1:2~1:4 Negative Online Inquiry
KO14652 RBPMS2 Knockout cell line (HEK293) Human RBPMS2 1:3~1:6 Negative Online Inquiry
KO14653 RBPMS2 Knockout cell line (A549) Human RBPMS2 1:3~1:4 Negative Online Inquiry

Background

RBPMS2 Gene Knockout Cell Lines are genetically engineered cell lines in which the RBPMS2 gene has been disrupted or "knocked out." The RBPMS2 (RNA binding protein with multiple splicing) gene plays a vital role in the regulation of alternative splicing and RNA metabolism, making these knockout models invaluable for understanding the functional significance of RBPMS2 in cellular processes. Through the use of CRISPR-Cas9 gene-editing technology, these cell lines enable researchers to study the impact of RBPMS2 absence on various physiological and pathological conditions, elucidating its role in tumorigenesis, neurodegenerative diseases, and developmental biology among others.

The primary function of RBPMS2 involves the binding of RNA and modulation of its expression and splicing profile, influencing gene expression dynamics. By providing a model in which RBPMS2 is absent, the knockout cell lines facilitate a clear differentiation in cellular responses, allowing researchers to dissect cellular pathways and identify potential regulatory networks impacted by this gene. These studies are crucial for theoretical research and real-world applications, including drug development and therapeutic targeting.

What sets RBPMS2 Gene Knockout Cell Lines apart from alternative models is their specificity and precision. Unlike traditional knockdown methods, which may only reduce gene function and not fully eliminate it, these knockout lines provide a definitive absence of the RBPMS2 protein, offering clearer insights into the biological roles it plays. Furthermore, these cell lines are ready-to-use and validated for consistent experimental results, saving valuable time for researchers aiming to expedite their studies.

The value of RBPMS2 Gene Knockout Cell Lines lies in their ability to provide a biologically relevant platform for discovery in both research and clinical applications. Researchers and clinicians can leverage the insights gained from these models to better understand disease mechanisms and to push forward therapeutic innovations.

At our company, we pride ourselves on our commitment to facilitating cutting-edge research through high-quality biological products. Our expertise in genetic engineering and cell line development ensures that researchers receive unparalleled tools designed to accelerate their innovative work.

Please note that all services are for research use only. Not intended for any clinical use.

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