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RBM47 Knockout Cell Lines

Gene: RBM47

Official Full Name: RNA binding motif protein 47provided by HGNC

Gene Summary: Enables enzyme binding activity; enzyme-substrate adaptor activity; and mRNA 3'-UTR binding activity. Involved in cytidine to uridine editing; positive regulation of type I interferon-mediated signaling pathway; and regulation of mRNA metabolic process. Located in cytoplasm and nucleus. Part of apolipoprotein B mRNA editing enzyme complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21679 RBM47 Knockout cell line (HeLa) Human RBM47 1:3~1:6 Negative Online Inquiry
KO21680 RBM47 Knockout cell line (HCT 116) Human RBM47 1:2~1:4 Negative Online Inquiry
KO21681 RBM47 Knockout cell line (HEK293) Human RBM47 1:3~1:6 Negative Online Inquiry
KO21682 RBM47 Knockout cell line (A549) Human RBM47 1:3~1:4 Negative Online Inquiry

Background

RBM47 Gene Knockout Cell Lines are genetically modified cellular models that are specifically engineered to lack the RNA-binding motif protein 47 (RBM47), which plays a crucial role in the post-transcriptional regulation of gene expression. By employing CRISPR-Cas9 gene editing technology, these cell lines provide researchers with a powerful tool to study the physiological and pathological roles of RBM47, including its involvement in various cellular processes such as RNA splicing, stability, and translation.

The primary mechanism of action for RBM47 involves its capacity to bind to specific RNA sequences, thereby influencing mRNA metabolism. Knockout of RBM47 allows researchers to dissect the consequences of its absence on cellular phenotypes, gene expression patterns, and RNA processing pathways, providing insights into disease mechanisms, particularly in cancer and neurological disorders. This capability to explore both basic biological functions and disease-driven processes highlights the scientific importance of these cell lines in accelerating research and facilitating novel therapeutic discoveries.

What sets the RBM47 Gene Knockout Cell Lines apart from traditional cell models is their unique ability to simulate the loss-of-function scenario, enabling scientists to observe alterations in gene expression and cellular behavior in a controlled environment. Unlike wild-type cell lines, these knockouts specifically eliminate RBM47, thus reducing background noise from other genes and enhancing the clarity of experimental results. This specificity increases the reliability of data obtained and improves the translational potential of findings to clinical applications.

For researchers and clinicians alike, the RBM47 Gene Knockout Cell Lines are invaluable resources that promote targeted investigations into gene function and regulation, ultimately aiding in the development of novel therapies. Their use can augment the understanding of complex biological systems and improve therapeutic strategies.

With years of experience in genetic engineering and a commitment to providing high-quality biological products, our company specializes in delivering innovative research tools that empower the scientific community. Our advanced technologies and rigorous quality control ensure that our RBM47 Gene Knockout Cell Lines meet the highest standards, making them a trusted choice for advancing cutting-edge research.

Please note that all services are for research use only. Not intended for any clinical use.

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