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RBM15B Knockout Cell Lines

Gene: RBM15B

Official Full Name: RNA binding motif protein 15Bprovided by HGNC

Gene Summary: Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26987 RBM15B Knockout cell line (HeLa) Human RBM15B 1:3~1:6 Negative Online Inquiry
KO26988 RBM15B Knockout cell line (HCT 116) Human RBM15B 1:2~1:4 Negative Online Inquiry
KO26989 RBM15B Knockout cell line (HEK293) Human RBM15B 1:3~1:6 Negative Online Inquiry
KO26990 RBM15B Knockout cell line (A549) Human RBM15B 1:3~1:4 Negative Online Inquiry

Background

RBM15B Gene Knockout Cell Lines represent a critical innovation in the field of genetic research, providing researchers with a powerful tool for dissecting the molecular pathways influenced by the RBM15B gene. These cell lines are genetically engineered to lack the RBM15B gene, allowing scientists to explore its role in post-transcriptional regulation and its implications in various biological processes, including cell differentiation, proliferation, and apoptosis. The knockout mechanism has been achieved through advanced CRISPR-Cas9 technology, which ensures precise modifications at the genomic level, thus maintaining high fidelity in genetic manipulation.

The key functions of RBM15B include its involvement in RNA splicing and dosage compensation, making it a significant player in gene expression regulation. By utilizing these knockout cell lines, researchers can elucidate the consequences of RBM15B deficiency on cellular function and pathways, providing insights that could lead to potential therapeutic targets in diseases where these processes are dysregulated.

The scientific importance of RBM15B Gene Knockout Cell Lines extends into various research areas, such as oncology, neurobiology, and developmental biology. In clinical settings, understanding the aberrations linked to RBM15B can facilitate the identification of biomarkers for disease progression and therapeutic responses, thus enhancing the precision of medical interventions.

In comparison to alternatives, RBM15B knockout cell lines offer unparalleled specificity and reliability in studying gene function without confounding variables typically associated with off-target effects. This level of precision allows for reproducible results that are critical in translational research and drug development.

For researchers and clinicians, the value of RBM15B Gene Knockout Cell Lines lies in their ability to drive discoveries that impact health outcomes while accelerating the pace of scientific innovation. By integrating rigorous quality assurance processes, our company has cemented its reputation as a leader in the provision of high-quality biological products that empower the scientific community. We deliver not just products, but solutions that are instrumental in advancing knowledge and improving patient care.

Please note that all services are for research use only. Not intended for any clinical use.

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