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RB1CC1 Knockout Cell Lines

Gene: RB1CC1

Official Full Name: RB1 inducible coiled-coil 1provided by HGNC

Gene Summary: The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00304 RB1CC1 Knockout cell line (HeLa) Human RB1CC1 1:3~1:6 Negative Online Inquiry
KO04423 RB1CC1 Knockout cell line (HCT 116) Human RB1CC1 1:2~1:4 Negative Online Inquiry
KO04424 RB1CC1 Knockout cell line (HEK293) Human RB1CC1 1:3~1:6 Negative Online Inquiry
KO04425 RB1CC1 Knockout cell line (A549) Human RB1CC1 1:3~1:4 Negative Online Inquiry

Background

RB1CC1 Gene Knockout Cell Lines represent a pivotal advancement in cellular research, specifically tailored for the functional analysis of the RB1CC1 gene. This product is characterized by a meticulously engineered disruption of the RB1CC1 gene, which encodes a protein integral to cellular processes such as autophagy, cell growth, and signaling pathways. By creating a knockout of this critical gene, researchers can directly observe the resultant phenotypic and molecular changes, allowing for a deeper understanding of RB1CC1's role in both normal physiology and pathological states.

The primary function of these knockout cell lines lies in their ability to facilitate the investigation of RB1CC1's involvement in cellular pathways and disease mechanisms. The absence of the RB1CC1 gene allows researchers to decipher alterations in cellular behavior and signaling patterns, which can have substantial implications for understanding various cancers, neurodegenerative disorders, and other conditions where autophagy is disrupted. By employing techniques such as Western blotting, qPCR, and flow cytometry, users can assess the impact of RB1CC1 deletion on cellular functions, enabling new insights into therapeutic targets.

The scientific importance of RB1CC1 Gene Knockout Cell Lines is underscored by their versatility in research and clinical applications. These lines serve as invaluable tools in drug screening, genetic studies, and the development of restorative therapies. The value of this product extends beyond mere research utility; it equips scientists with the means to explore potential interventions in diseases linked to dysfunctional RB1CC1 signaling.

Compared to alternatives such as siRNA-mediated knockdowns, RB1CC1 knockout cell lines provide a stable and permanent genetic alteration, eliminating concerns over transient expression and variability. This permanence ensures that experimental results are reproducible and accurate over extended periods, which is often a critical factor in advanced research paradigms.

For researchers and clinicians seeking cutting-edge solutions, RB1CC1 Gene Knockout Cell Lines offer unique advantages, including reliability, specificity, and comprehensive support from our team of experts. Our long-standing commitment to delivering high-quality biological products ensures that customers receive not only superior reagents but also unparalleled technical guidance through their research journey. Engaging with our offerings means partnering with a leader in the biological solutions sector dedicated to advancing scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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