Gene: RASSF2
Official Full Name: Ras association domain family member 2provided by HGNC
Gene Summary: This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32791 | RASSF2 Knockout cell line (HCT 116) | Human | RASSF2 | 1:2~1:4 | Negative | Online Inquiry |
KO32792 | RASSF2 Knockout cell line (HEK293) | Human | RASSF2 | 1:3~1:6 | Negative | Online Inquiry |
KO32793 | RASSF2 Knockout cell line (A549) | Human | RASSF2 | 1:3~1:4 | Negative | Online Inquiry |
RASSF2 Gene Knockout Cell Lines are a unique cellular platform specifically designed to facilitate in-depth studies of the RASSF2 gene, a critical player in cell cycle regulation and tumor suppression. These genetically modified cell lines have undergone targeted gene disruption using CRISPR-Cas9 technology, effectively knocking out the RASSF2 gene. This allows researchers to examine the biological consequences of its loss, particularly in the context of cancer progression and cellular signaling pathways.
The key functions of the RASSF2 gene involve the regulation of mitotic processes and apoptosis, acting as a scaffold for various signaling proteins that influence tumor development. By utilizing these knockout cell lines, scientists can investigate the mechanisms by which RASSF2 modulates pathways such as the hippo signaling cascade, thereby uncovering the complex interactions that lead to abnormal cell proliferation. Furthermore, these cell lines serve as valuable tools for exploring potential therapeutic targets, making them indispensable in both research and clinical environments.
What sets RASSF2 Gene Knockout Cell Lines apart from traditional cell lines is their precision and specificity in gene editing, enabling reproducible and reliable results that enhance the quality of experimental outcomes. This is particularly important in cancer research where understanding the genetic underpinnings of tumor behavior can lead to the development of targeted therapies. Additionally, these knockout cell lines are readily adaptable for high-throughput screening, promoting efficiency in drug discovery and functional genomics studies.
The value of RASSF2 Gene Knockout Cell Lines extends beyond their immediate applications in research; they empower users by providing insights into the roles of tumor suppressor genes and the molecular mechanisms underlying various malignancies. This knowledge not only advances scientific understanding but also paves the way for innovative cancer treatment strategies.
With our company’s extensive expertise in genetic engineering and commitment to providing high-quality biological products, we are proud to offer RASSF2 Gene Knockout Cell Lines as a vital resource for researchers and clinicians dedicated to unraveling the complexities of cancer biology and pursuing novel therapeutic avenues.
Please note that all services are for research use only. Not intended for any clinical use.
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