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RASGEF1C Knockout Cell Lines

Gene: RASGEF1C

Official Full Name: RasGEF domain family member 1Cprovided by HGNC

Gene Summary: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21095 RASGEF1C Knockout cell line (HEK293) Human RASGEF1C 1:3~1:6 Negative Online Inquiry

Background

RASGEF1C Gene Knockout Cell Lines are engineered cellular models specifically designed to study the biological functions and regulatory mechanisms associated with the RASGEF1C gene. This gene encodes a guanine nucleotide exchange factor (GEF) that activates RAS proteins, which are pivotal in signal transduction pathways influencing cell proliferation, differentiation, and survival. The knockout of RASGEF1C allows researchers to dissect the gene's contribution to various cellular processes and its implications in disease states, particularly in cancer biology where aberrant RAS signaling is frequently implicated.

The key functions of RASGEF1C Gene Knockout Cell Lines revolve around their ability to facilitate gain-of-function or loss-of-function studies on RAS signaling pathways. By knocking out this gene, researchers can observe changes in RAS activation and downstream signaling cascades, providing insights into cellular behavior under normal and pathological conditions. This cellular tool is crucial for elucidating the mechanisms of drug resistance, tumorigenesis, and the effects of experimental therapies targeting the RAS pathway.

In research and clinical settings, RASGEF1C Gene Knockout Cell Lines are invaluable for basic research, drug discovery, and translational studies focused on cancer therapies. The specificity of these cell lines allows for high-throughput screening of potential anticancer agents and the exploration of novel therapeutic strategies aimed at modulating RAS signaling.

One of the significant advantages of RASGEF1C Gene Knockout Cell Lines over traditional models is the precision of gene editing technology, which ensures high fidelity in targeting the gene without off-target effects. This precision enhances the reproducibility and reliability of experimental outcomes, giving researchers confidence in their findings. Furthermore, the availability of these knockout cell lines supports a diverse range of experimental designs, enabling comprehensive studies on the functions and pathways driven by RAS proteins.

Overall, RASGEF1C Gene Knockout Cell Lines represent a powerful asset for scientists seeking to unravel the complexities of RAS signaling in health and disease. Our company is committed to providing high-quality, innovative biological products, with a focus on facilitating groundbreaking research and clinical advancements in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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