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RAPGEF6 Knockout Cell Lines

Gene: RAPGEF6

Official Full Name: Rap guanine nucleotide exchange factor 6provided by HGNC

Gene Summary: Enables several functions, including GTP-dependent protein binding activity; guanyl-nucleotide exchange factor activity; and phosphatidic acid binding activity. Involved in microvillus assembly; positive regulation of GTPase activity; and protein localization to plasma membrane. Located in several cellular components, including apical plasma membrane; centrosome; and endocytic vesicle. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08770 RAPGEF6 Knockout cell line (HeLa) Human RAPGEF6 1:3~1:6 Negative Online Inquiry
KO08771 RAPGEF6 Knockout cell line (HCT 116) Human RAPGEF6 1:2~1:4 Negative Online Inquiry
KO08772 RAPGEF6 Knockout cell line (HEK293) Human RAPGEF6 1:3~1:6 Negative Online Inquiry
KO08773 RAPGEF6 Knockout cell line (A549) Human RAPGEF6 1:3~1:4 Negative Online Inquiry

Background

RAPGEF6 Gene Knockout Cell Lines are specialized cellular models designed to study the function of the RAPGEF6 gene, which encodes a guanine nucleotide exchange factor involved in the activation of specific G-proteins. These knockout cell lines have been engineered through targeted gene editing techniques, enabling researchers to create a functional deficiency in RAPGEF6. By eliminating this gene, the cell lines provide a unique platform to investigate the regulatory pathways influenced by RAPGEF6 and its role in various cellular processes such as signal transduction, cell proliferation, and migration.

The key functions of the RAPGEF6 Gene Knockout Cell Lines centre around investigating the downstream effects associated with the loss of RAPGEF6 activity. By analyzing these cell lines, researchers can elucidate the mechanisms by which RAPGEF6 modulates critical biological processes and how its dysregulation may contribute to various diseases, including cancer and neurodegenerative disorders. This research is invaluable in identifying potential therapeutic targets and the underlying molecular mechanisms involved in disease pathology.

The scientific importance of RAPGEF6 Gene Knockout Cell Lines extends to both fundamental research and clinical applications, including drug discovery and biomarker identification. Their utility in the lab allows for the assessment of drug efficacy and the potential for personalized medicine approaches where responses can be analyzed in a gene-specific manner.

Compared to other knockout models, the RAPGEF6 Gene Knockout Cell Lines offer specificity and precision in studying the gene's unique biological functions. The ease of customization and integration with high-throughput screening technologies further enhances their compatibility with diverse research objectives.

For researchers and clinicians focused on advancing our understanding of G-protein signaling pathways, these cell lines present a valuable toolset for conducting cutting-edge experiments. Their ability to provide insights into both health and disease makes them essential for anyone exploring therapeutic innovations or the intricate biological frameworks involved.

Our company specializes in providing high-quality biological products supported by extensive expertise in molecular biology and cell line development. We are committed to empowering researchers with innovative tools that facilitate impactful scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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